PROTAGENIC THERAPEUTICS INC

Ticker: PTIXW CUSIP: 74365N111 Class: *W EXP 04/26/202

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025
Shares 15,533 Value ($000) $0 Avg Close — Range —
Q3 2025
Shares 12,352 Value ($000) $0 Avg Close — Range —
Q2 2025
Shares 11,242 Value ($000) $1 Avg Close — Range —
Q4 2024
Shares 17,500 Value ($000) $0 Avg Close — Range —