PROTEOSTASIS THERAPEUTICS IN

CUSIP: 74373B109 Class: COM

PRICE T ROWE ASSOCIATES INC /MD/'s Holding History (CIK: 0000080255)

Note: Option positions (PUT/CALL) are excluded.

Q3 2019
Shares 44,974 Value ($000) $38 Avg Close — Range —
Q2 2019
Shares 134,904 Value ($000) $132 Avg Close — Range —
Q1 2019
Shares 135,458 Value ($000) $171 Avg Close — Range —
Q4 2018
Shares 1,069,020 Value ($000) $3,464 Avg Close — Range —
Q3 2018
Shares 135,179 Value ($000) $326 Avg Close — Range —
Q2 2018
Shares 135,079 Value ($000) $377 Avg Close — Range —
Q1 2018
Shares 768,804 Value ($000) $3,652 Avg Close — Range —
Q4 2017
Shares 158,924 Value ($000) $927 Avg Close — Range —
Q3 2017
Shares 158,924 Value ($000) $334 Avg Close — Range —
Q2 2017
Shares 698,924 Value ($000) $3,271 Avg Close — Range —
Q1 2017
Shares 940,689 Value ($000) $7,356 Avg Close — Range —
Q4 2016
Shares 212,817 Value ($000) $2,609 Avg Close — Range —
Q3 2016
Shares 214,717 Value ($000) $3,347 Avg Close — Range —