PROTEOSTASIS THERAPEUTICS IN

CUSIP: 74373B109 Class: COM

FIL Ltd's Holding History (CIK: 0000318989)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 652,316 Value ($000) $1,572 Avg Close — Range —
Q2 2018
Shares 652,316 Value ($000) $1,820 Avg Close — Range —
Q1 2018
Shares 652,316 Value ($000) $3,099 Avg Close — Range —
Q4 2017
Shares 652,316 Value ($000) $3,803 Avg Close — Range —
Q3 2017
Shares 652,316 Value ($000) $1,370 Avg Close — Range —
Q2 2017
Shares 652,316 Value ($000) $3,053 Avg Close — Range —
Q1 2017
Shares 652,316 Value ($000) $5,101 Avg Close — Range —
Q4 2016
Shares 652,316 Value ($000) $7,997 Avg Close — Range —
Q3 2016
Shares 652,316 Value ($000) $10,170 Avg Close — Range —