PROTEOSTASIS THERAPEUTICS IN

CUSIP: 74373B109 Class: COM

STATE OF WISCONSIN INVESTMENT BOARD's Holding History (CIK: 0000854157)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 49,000 Value ($000) $62 Avg Close — Range —
Q4 2018
Shares 26,400 Value ($000) $86 Avg Close — Range —