PROTEOSTASIS THERAPEUTICS IN

CUSIP: 74373B109 Class: COM

CHARLES SCHWAB INVESTMENT MANAGEMENT INC's Holding History (CIK: 0000884546)

Note: Option positions (PUT/CALL) are excluded.

Q1 2019
Shares 74,920 Value ($000) $95 Avg Close — Range —
Q4 2018
Shares 74,920 Value ($000) $243 Avg Close — Range —
Q3 2018
Shares 46,900 Value ($000) $114 Avg Close — Range —
Q2 2018
Shares 46,900 Value ($000) $131 Avg Close — Range —
Q1 2018
Shares 18,300 Value ($000) $87 Avg Close — Range —
Q4 2017
Shares 18,300 Value ($000) $107 Avg Close — Range —
Q3 2017
Shares 18,300 Value ($000) $39 Avg Close — Range —
Q2 2017
Shares 18,300 Value ($000) $86 Avg Close — Range —
Q1 2017
Shares 28,300 Value ($000) $222 Avg Close — Range —
Q4 2016
Shares 28,300 Value ($000) $347 Avg Close — Range —
Q3 2016
Shares 10,000 Value ($000) $156 Avg Close — Range —
Q2 2016
Shares 10,000 Value ($000) $122 Avg Close — Range —