PROTEOSTASIS THERAPEUTICS IN

CUSIP: 74373B109 Class: COM

DEERFIELD MANAGEMENT COMPANY, L.P.'s Holding History (CIK: 0001009258)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 419,000 Value ($000) $1,358 Avg Close — Range —
Q2 2017
Shares 17,251 Value ($000) $81 Avg Close — Range —
Q4 2016
Shares 186,000 Value ($000) $2,280 Avg Close — Range —
Q3 2016
Shares 186,000 Value ($000) $2,900 Avg Close — Range —