PROTEOSTASIS THERAPEUTICS IN

CUSIP: 74373B109 Class: COM

PERCEPTIVE ADVISORS LLC's Holding History (CIK: 0001224962)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 344,550 Value ($000) $5,372 Avg Close — Range —
Q2 2016
Shares 250,000 Value ($000) $3,033 Avg Close — Range —
Q1 2016
Shares 250,000 Value ($000) $2,410 Avg Close — Range —