PROTEOSTASIS THERAPEUTICS IN

CUSIP: 74373B109 Class: COM

SIMPLEX TRADING, LLC's Holding History (CIK: 0001488542)

Note: Option positions (PUT/CALL) are excluded.

Q3 2020
Shares 11,991 Value ($000) $13 Avg Close — Range —
Q2 2020
Shares 32,247 Value ($000) $44 Avg Close — Range —
Q1 2020
Shares 62,341 Value ($000) $71 Avg Close — Range —
Q4 2019
Shares 79,412 Value ($000) $181 Avg Close — Range —
Q3 2019
Shares 9,000 Value ($000) $7 Avg Close — Range —
Q2 2019
Shares 24,968 Value ($000) $24 Avg Close — Range —
Q1 2019
Shares 94,101 Value ($000) $118 Avg Close — Range —
Q2 2018
Shares 1,853 Value ($000) $5 Avg Close — Range —