PROTEOSTASIS THERAPEUTICS IN

CUSIP: 74373B109 Class: COM

Candriam S.C.A.'s Holding History (CIK: 0001537014)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 250,000 Value ($000) $810 Avg Close — Range —
Q3 2017
Shares 75,000 Value ($000) $158 Avg Close — Range —
Q2 2017
Shares 75,000 Value ($000) $351 Avg Close — Range —
Q1 2017
Shares 75,000 Value ($000) $587 Avg Close — Range —
Q4 2016
Shares 45,000 Value ($000) $552 Avg Close — Range —