PROVECTUS BIOPHARMACEUTICALS

Ticker: PVCT CUSIP: 74373P108 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016

Shares 11,466 Value ($000) $4 Avg Close $0.38 Range $0.31 - $0.54

Q1 2016

Shares 21,811 Value ($000) $8 Avg Close $0.41 Range $0.35 - $0.53

Q4 2014

Shares 12,490 Value ($000) $10 Avg Close $0.91 Range $0.76 - $1.10

Period	Shares	Value ($000)	Average Close	Price Range
Q2 2016	11,466	$4	$0.38	$0.31 - $0.54
Q1 2016	21,811	$8	$0.41	$0.35 - $0.53
Q4 2014	12,490	$10	$0.91	$0.76 - $1.10