PULSE BIOSCIENCES INC

Ticker: PLSE CUSIP: 74587B101 Class: Common Stock

TWO SIGMA ADVISERS, LP's Holding History (CIK: 0001478735)

Note: Option positions (PUT/CALL) are excluded.

Q1 2022

Shares 14,298 Value ($000) $69 Avg Close $8.18 Range $4.14 - $15.38

Q4 2021

Shares 16,798 Value ($000) $249 Avg Close $19.91 Range $14.11 - $24.58

Q3 2021

Shares 32,798 Value ($000) $708 Avg Close $21.51 Range $16.66 - $29.16

Q2 2021

Shares 36,398 Value ($000) $597 Avg Close $19.03 Range $14.59 - $24.20

Period	Shares	Value ($000)	Average Close	Price Range
Q1 2022	14,298	$69	$8.18	$4.14 - $15.38
Q4 2021	16,798	$249	$19.91	$14.11 - $24.58
Q3 2021	32,798	$708	$21.51	$16.66 - $29.16
Q2 2021	36,398	$597	$19.03	$14.59 - $24.20