PYXIS ONCOLOGY INC

Ticker: PYXS CUSIP: 747324101 Class: Common Stock

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2021

Shares 10,367 Value ($000) $114 Avg Close $11.45 Range $7.90 - $19.00

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2021	10,367	$114	$11.45	$7.90 - $19.00