REGENERON PHARMACEUTICALS

Ticker: REGN CUSIP: 75886F107 Class: COM

CAISSE DE DEPOT ET PLACEMENT DU QUEBEC's Holding History (CIK: 0000898286)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 342,319 Value ($000) $264,226 Avg Close $678.68 Range $540.32 - $792.77

Q3 2025

Shares 462,502 Value ($000) $260,051 Avg Close $564.28 Range $519.56 - $609.69

Q2 2025

Shares 214,722 Value ($000) $112,729 Avg Close $556.12 Range $475.17 - $638.52

Q1 2025

Shares 222,614 Value ($000) $141,188 Avg Close $684.44 Range $615.89 - $745.12

Q4 2024

Shares 310,153 Value ($000) $220,931 Avg Close $834.60 Range $689.18 - $1055.74

Q3 2024

Shares 194,625 Value ($000) $204,598 Avg Close $1106.73 Range $1002.85 - $1204.52

Q2 2024

Shares 138,797 Value ($000) $145,880 Avg Close $964.05 Range $870.40 - $1075.21

Q1 2024

Shares 228,001 Value ($000) $219,449 Avg Close $945.64 Range $866.58 - $992.82

Q4 2023

Shares 260,166 Value ($000) $228,501 Avg Close $818.96 Range $764.95 - $894.90

Q3 2023

Shares 148,071 Value ($000) $121,857 Avg Close $781.58 Range $684.72 - $842.83

Q2 2023

Shares 180,258 Value ($000) $129,523 Avg Close $766.75 Range $681.03 - $832.93

Q1 2023

Shares 165,152 Value ($000) $135,700 Avg Close $750.05 Range $664.32 - $830.39

Q4 2022

Shares 107,416 Value ($000) $77,500 Avg Close $733.79 Range $690.81 - $774.70

Q3 2022

Shares 125,461 Value ($000) $86,426 Avg Close $625.92 Range $560.71 - $750.51

Q2 2022

Shares 109,813 Value ($000) $64,914 Avg Close $646.43 Range $535.04 - $743.30

Q1 2022

Shares 163,663 Value ($000) $114,306 Avg Close $629.16 Range $589.59 - $706.29

Q4 2021

Shares 184,517 Value ($000) $116,526 Avg Close $611.44 Range $536.21 - $670.14

Q3 2021

Shares 122,453 Value ($000) $74,106 Avg Close $617.39 Range $551.89 - $682.83

Q2 2021

Shares 39,665 Value ($000) $22,154 Avg Close $503.83 Range $466.78 - $566.85

Q1 2021

Shares 7,229 Value ($000) $3,420 Avg Close $484.19 Range $438.57 - $555.83

Q4 2020

Shares 7,540 Value ($000) $3,643 Avg Close $536.82 Range $468.18 - $616.55

Q3 2020

Shares 10,749 Value ($000) $6,017 Avg Close $602.99 Range $537.02 - $660.97

Q2 2020

Shares 11,449 Value ($000) $7,140 Avg Close $564.49 Range $473.82 - $642.77

Q1 2020

Shares 15,549 Value ($000) $7,592 Avg Close $410.21 Range $326.32 - $515.14

Q4 2019

Shares 11,249 Value ($000) $4,224 Avg Close $334.59 Range $270.76 - $380.14

Q3 2019

Shares 11,149 Value ($000) $3,093 Avg Close $294.28 Range $269.87 - $318.99

Q2 2019

Shares 10,849 Value ($000) $3,396 Avg Close $331.08 Range $293.64 - $413.60

Q1 2019

Shares 10,049 Value ($000) $4,126 Avg Close $409.51 Range $363.99 - $439.56

Q4 2018

Shares 8,749 Value ($000) $3,268 Avg Close $364.00 Range $325.77 - $407.74

Q3 2018

Shares 4,149 Value ($000) $1,676 Avg Close $378.49 Range $340.69 - $414.19

Q2 2018

Shares 4,549 Value ($000) $1,569 Avg Close $311.03 Range $280.34 - $347.31

Q1 2018

Shares 9,649 Value ($000) $3,323 Avg Close $345.90 Range $311.80 - $394.59

Q4 2017

Shares 8,149 Value ($000) $3,064 Avg Close $402.77 Range $351.19 - $474.37

Q3 2017

Shares 8,649 Value ($000) $3,883 Avg Close $473.21 Range $424.12 - $523.22

Q2 2017

Shares 8,449 Value ($000) $4,138 Avg Close $435.19 Range $358.01 - $540.55

Q1 2017

Shares 7,749 Value ($000) $3,006 Avg Close $368.62 Range $338.21 - $399.00

Q4 2016

Shares 7,449 Value ($000) $2,731 Avg Close $378.17 Range $323.56 - $450.46

Q3 2016

Shares 9,149 Value ($000) $3,678 Avg Close $398.92 Range $346.51 - $441.54

Q2 2016

Shares 9,749 Value ($000) $3,405 Avg Close $383.00 Range $327.27 - $431.54

Q1 2016

Shares 4,349 Value ($000) $1,568 Avg Close $409.79 Range $347.04 - $529.97

Q4 2015

Shares 13,000 Value ($000) $7,057 Avg Close $538.82 Range $445.63 - $589.32

Q3 2015

Shares 14,200 Value ($000) $6,605 Avg Close $534.07 Range $433.12 - $602.59

Q2 2015

Shares 3,100 Value ($000) $1,581 Avg Close $485.93 Range $431.08 - $541.00

Q1 2015

Shares 32,600 Value ($000) $14,718 Avg Close $421.46 Range $390.83 - $492.77

Q4 2014

Shares 36,000 Value ($000) $14,769 Avg Close $391.09 Range $318.29 - $435.23

Q3 2014

Shares 39,000 Value ($000) $14,060 Avg Close $333.32 Range $283.49 - $367.27

Q2 2014

Shares 43,600 Value ($000) $12,316 Avg Close $294.74 Range $268.01 - $318.24

Q1 2014

Shares 45,200 Value ($000) $13,573 Avg Close $306.39 Range $261.52 - $350.55

Q4 2013

Shares 44,200 Value ($000) $12,166 Avg Close $286.03 Range $256.27 - $317.74

Q3 2013

Shares 50,200 Value ($000) $15,706 Avg Close $261.58 Range $224.53 - $318.07

Q2 2013

Shares 58,400 Value ($000) $13,133 Avg Close $231.58 Range $176.14 - $282.42

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	342,319	$264,226	$678.68	$540.32 - $792.77
Q3 2025	462,502	$260,051	$564.28	$519.56 - $609.69
Q2 2025	214,722	$112,729	$556.12	$475.17 - $638.52
Q1 2025	222,614	$141,188	$684.44	$615.89 - $745.12
Q4 2024	310,153	$220,931	$834.60	$689.18 - $1055.74
Q3 2024	194,625	$204,598	$1106.73	$1002.85 - $1204.52
Q2 2024	138,797	$145,880	$964.05	$870.40 - $1075.21
Q1 2024	228,001	$219,449	$945.64	$866.58 - $992.82
Q4 2023	260,166	$228,501	$818.96	$764.95 - $894.90
Q3 2023	148,071	$121,857	$781.58	$684.72 - $842.83
Q2 2023	180,258	$129,523	$766.75	$681.03 - $832.93
Q1 2023	165,152	$135,700	$750.05	$664.32 - $830.39
Q4 2022	107,416	$77,500	$733.79	$690.81 - $774.70
Q3 2022	125,461	$86,426	$625.92	$560.71 - $750.51
Q2 2022	109,813	$64,914	$646.43	$535.04 - $743.30
Q1 2022	163,663	$114,306	$629.16	$589.59 - $706.29
Q4 2021	184,517	$116,526	$611.44	$536.21 - $670.14
Q3 2021	122,453	$74,106	$617.39	$551.89 - $682.83
Q2 2021	39,665	$22,154	$503.83	$466.78 - $566.85
Q1 2021	7,229	$3,420	$484.19	$438.57 - $555.83
Q4 2020	7,540	$3,643	$536.82	$468.18 - $616.55
Q3 2020	10,749	$6,017	$602.99	$537.02 - $660.97
Q2 2020	11,449	$7,140	$564.49	$473.82 - $642.77
Q1 2020	15,549	$7,592	$410.21	$326.32 - $515.14
Q4 2019	11,249	$4,224	$334.59	$270.76 - $380.14
Q3 2019	11,149	$3,093	$294.28	$269.87 - $318.99
Q2 2019	10,849	$3,396	$331.08	$293.64 - $413.60
Q1 2019	10,049	$4,126	$409.51	$363.99 - $439.56
Q4 2018	8,749	$3,268	$364.00	$325.77 - $407.74
Q3 2018	4,149	$1,676	$378.49	$340.69 - $414.19
Q2 2018	4,549	$1,569	$311.03	$280.34 - $347.31
Q1 2018	9,649	$3,323	$345.90	$311.80 - $394.59
Q4 2017	8,149	$3,064	$402.77	$351.19 - $474.37
Q3 2017	8,649	$3,883	$473.21	$424.12 - $523.22
Q2 2017	8,449	$4,138	$435.19	$358.01 - $540.55
Q1 2017	7,749	$3,006	$368.62	$338.21 - $399.00
Q4 2016	7,449	$2,731	$378.17	$323.56 - $450.46
Q3 2016	9,149	$3,678	$398.92	$346.51 - $441.54
Q2 2016	9,749	$3,405	$383.00	$327.27 - $431.54
Q1 2016	4,349	$1,568	$409.79	$347.04 - $529.97
Q4 2015	13,000	$7,057	$538.82	$445.63 - $589.32
Q3 2015	14,200	$6,605	$534.07	$433.12 - $602.59
Q2 2015	3,100	$1,581	$485.93	$431.08 - $541.00
Q1 2015	32,600	$14,718	$421.46	$390.83 - $492.77
Q4 2014	36,000	$14,769	$391.09	$318.29 - $435.23
Q3 2014	39,000	$14,060	$333.32	$283.49 - $367.27
Q2 2014	43,600	$12,316	$294.74	$268.01 - $318.24
Q1 2014	45,200	$13,573	$306.39	$261.52 - $350.55
Q4 2013	44,200	$12,166	$286.03	$256.27 - $317.74
Q3 2013	50,200	$15,706	$261.58	$224.53 - $318.07
Q2 2013	58,400	$13,133	$231.58	$176.14 - $282.42