REGENERON PHARMACEUTICALS

Ticker: REGN CUSIP: 75886F107 Class: COM

GREAT LAKES ADVISORS, LLC's Holding History (CIK: 0001078013)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,833 Value ($000) $1,415 Avg Close $678.68 Range $540.32 - $792.77

Q3 2025

Shares 1,825 Value ($000) $1,026 Avg Close $564.28 Range $519.56 - $609.69

Q3 2024

Shares 1,418 Value ($000) $1,491 Avg Close $1106.73 Range $1002.85 - $1204.52

Q2 2024

Shares 1,775 Value ($000) $1,866 Avg Close $964.05 Range $870.40 - $1075.21

Q2 2023

Shares 1,759 Value ($000) $1,264 Avg Close $766.75 Range $681.03 - $832.93

Q1 2023

Shares 1,789 Value ($000) $1,470 Avg Close $750.05 Range $664.32 - $830.39

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,833	$1,415	$678.68	$540.32 - $792.77
Q3 2025	1,825	$1,026	$564.28	$519.56 - $609.69
Q3 2024	1,418	$1,491	$1106.73	$1002.85 - $1204.52
Q2 2024	1,775	$1,866	$964.05	$870.40 - $1075.21
Q2 2023	1,759	$1,264	$766.75	$681.03 - $832.93
Q1 2023	1,789	$1,470	$750.05	$664.32 - $830.39