REGENERON PHARMACEUTICALS

Ticker: REGN CUSIP: 75886F107 Class: COM

HOWLAND CAPITAL MANAGEMENT LLC's Holding History (CIK: 0001079112)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 37,860 Value ($000) $29,223 Avg Close $678.68 Range $540.32 - $792.77

Q3 2025

Shares 35,685 Value ($000) $20,065 Avg Close $564.28 Range $519.56 - $609.69

Q2 2025

Shares 31,795 Value ($000) $16,692 Avg Close $556.12 Range $475.17 - $638.52

Q1 2025

Shares 26,688 Value ($000) $16,926 Avg Close $684.44 Range $615.89 - $745.12

Q4 2024

Shares 15,437 Value ($000) $10,996 Avg Close $834.60 Range $689.18 - $1055.74

Q3 2024

Shares 1,258 Value ($000) $1,322 Avg Close $1106.73 Range $1002.85 - $1204.52

Q2 2024

Shares 1,315 Value ($000) $1,382 Avg Close $964.05 Range $870.40 - $1075.21

Q1 2024

Shares 1,333 Value ($000) $1,283 Avg Close $945.64 Range $866.58 - $992.82

Q4 2023

Shares 1,333 Value ($000) $1,171 Avg Close $818.96 Range $764.95 - $894.90

Q3 2023

Shares 1,341 Value ($000) $1,104 Avg Close $781.58 Range $684.72 - $842.83

Q2 2023

Shares 1,349 Value ($000) $969 Avg Close $766.75 Range $681.03 - $832.93

Q1 2023

Shares 1,353 Value ($000) $1,112 Avg Close $750.05 Range $664.32 - $830.39

Q4 2022

Shares 1,436 Value ($000) $1,036 Avg Close $733.79 Range $690.81 - $774.70

Q3 2022

Shares 1,476 Value ($000) $1,017 Avg Close $625.92 Range $560.71 - $750.51

Q2 2022

Shares 944 Value ($000) $558 Avg Close $646.43 Range $535.04 - $743.30

Q1 2022

Shares 959 Value ($000) $670 Avg Close $629.16 Range $589.59 - $706.29

Q4 2021

Shares 869 Value ($000) $549 Avg Close $611.44 Range $536.21 - $670.14

Q3 2021

Shares 907 Value ($000) $549 Avg Close $617.39 Range $551.89 - $682.83

Q2 2021

Shares 907 Value ($000) $507 Avg Close $503.83 Range $466.78 - $566.85

Q1 2021

Shares 912 Value ($000) $432 Avg Close $484.19 Range $438.57 - $555.83

Q4 2020

Shares 819 Value ($000) $396 Avg Close $536.82 Range $468.18 - $616.55

Q3 2020

Shares 819 Value ($000) $458 Avg Close $602.99 Range $537.02 - $660.97

Q2 2020

Shares 819 Value ($000) $511 Avg Close $564.49 Range $473.82 - $642.77

Q1 2020

Shares 879 Value ($000) $429 Avg Close $410.21 Range $326.32 - $515.14

Q4 2019

Shares 967 Value ($000) $363 Avg Close $334.59 Range $270.76 - $380.14

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	37,860	$29,223	$678.68	$540.32 - $792.77
Q3 2025	35,685	$20,065	$564.28	$519.56 - $609.69
Q2 2025	31,795	$16,692	$556.12	$475.17 - $638.52
Q1 2025	26,688	$16,926	$684.44	$615.89 - $745.12
Q4 2024	15,437	$10,996	$834.60	$689.18 - $1055.74
Q3 2024	1,258	$1,322	$1106.73	$1002.85 - $1204.52
Q2 2024	1,315	$1,382	$964.05	$870.40 - $1075.21
Q1 2024	1,333	$1,283	$945.64	$866.58 - $992.82
Q4 2023	1,333	$1,171	$818.96	$764.95 - $894.90
Q3 2023	1,341	$1,104	$781.58	$684.72 - $842.83
Q2 2023	1,349	$969	$766.75	$681.03 - $832.93
Q1 2023	1,353	$1,112	$750.05	$664.32 - $830.39
Q4 2022	1,436	$1,036	$733.79	$690.81 - $774.70
Q3 2022	1,476	$1,017	$625.92	$560.71 - $750.51
Q2 2022	944	$558	$646.43	$535.04 - $743.30
Q1 2022	959	$670	$629.16	$589.59 - $706.29
Q4 2021	869	$549	$611.44	$536.21 - $670.14
Q3 2021	907	$549	$617.39	$551.89 - $682.83
Q2 2021	907	$507	$503.83	$466.78 - $566.85
Q1 2021	912	$432	$484.19	$438.57 - $555.83
Q4 2020	819	$396	$536.82	$468.18 - $616.55
Q3 2020	819	$458	$602.99	$537.02 - $660.97
Q2 2020	819	$511	$564.49	$473.82 - $642.77
Q1 2020	879	$429	$410.21	$326.32 - $515.14
Q4 2019	967	$363	$334.59	$270.76 - $380.14