REGENERON PHARMACEUTICALS

Ticker: REGN CUSIP: 75886F107 Class: COM

GATEWAY INVESTMENT ADVISERS LLC's Holding History (CIK: 0001114618)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 464 Value ($000) $358 Avg Close $678.68 Range $540.32 - $792.77

Q3 2025

Shares 445 Value ($000) $250 Avg Close $564.28 Range $519.56 - $609.69

Q2 2025

Shares 612 Value ($000) $321 Avg Close $556.12 Range $475.17 - $638.52

Q1 2025

Shares 925 Value ($000) $587 Avg Close $684.44 Range $615.89 - $745.12

Q4 2024

Shares 812 Value ($000) $578 Avg Close $834.60 Range $689.18 - $1055.74

Q3 2024

Shares 1,113 Value ($000) $1,170 Avg Close $1106.73 Range $1002.85 - $1204.52

Q2 2024

Shares 947 Value ($000) $995 Avg Close $964.05 Range $870.40 - $1075.21

Q1 2024

Shares 1,337 Value ($000) $1,287 Avg Close $945.64 Range $866.58 - $992.82

Q4 2023

Shares 1,176 Value ($000) $1,033 Avg Close $818.96 Range $764.95 - $894.90

Q3 2023

Shares 877 Value ($000) $722 Avg Close $781.58 Range $684.72 - $842.83

Q2 2023

Shares 915 Value ($000) $657 Avg Close $766.75 Range $681.03 - $832.93

Q1 2023

Shares 973 Value ($000) $799 Avg Close $750.05 Range $664.32 - $830.39

Q4 2022

Shares 1,001 Value ($000) $722 Avg Close $733.79 Range $690.81 - $774.70

Q3 2022

Shares 910 Value ($000) $627 Avg Close $625.92 Range $560.71 - $750.51

Q2 2022

Shares 972 Value ($000) $575 Avg Close $646.43 Range $535.04 - $743.30

Q1 2022

Shares 951 Value ($000) $664 Avg Close $629.16 Range $589.59 - $706.29

Q4 2021

Shares 1,104 Value ($000) $697 Avg Close $611.44 Range $536.21 - $670.14

Q3 2021

Shares 1,128 Value ($000) $683 Avg Close $617.39 Range $551.89 - $682.83

Q2 2021

Shares 1,153 Value ($000) $644 Avg Close $503.83 Range $466.78 - $566.85

Q1 2021

Shares 1,207 Value ($000) $571 Avg Close $484.19 Range $438.57 - $555.83

Q4 2020

Shares 1,167 Value ($000) $564 Avg Close $536.82 Range $468.18 - $616.55

Q3 2020

Shares 1,200 Value ($000) $672 Avg Close $602.99 Range $537.02 - $660.97

Q2 2020

Shares 1,292 Value ($000) $806 Avg Close $564.49 Range $473.82 - $642.77

Q1 2020

Shares 1,284 Value ($000) $627 Avg Close $410.21 Range $326.32 - $515.14

Q4 2019

Shares 1,006 Value ($000) $378 Avg Close $334.59 Range $270.76 - $380.14

Q3 2019

Shares 1,231 Value ($000) $341 Avg Close $294.28 Range $269.87 - $318.99

Q2 2019

Shares 3,342 Value ($000) $1,046 Avg Close $331.08 Range $293.64 - $413.60

Q1 2019

Shares 3,571 Value ($000) $1,466 Avg Close $409.51 Range $363.99 - $439.56

Q4 2018

Shares 3,345 Value ($000) $1,249 Avg Close $364.00 Range $325.77 - $407.74

Q3 2018

Shares 3,322 Value ($000) $1,342 Avg Close $378.49 Range $340.69 - $414.19

Q2 2018

Shares 3,370 Value ($000) $1,163 Avg Close $311.03 Range $280.34 - $347.31

Q1 2018

Shares 4,519 Value ($000) $1,556 Avg Close $345.90 Range $311.80 - $394.59

Q4 2017

Shares 4,857 Value ($000) $1,826 Avg Close $402.77 Range $351.19 - $474.37

Q3 2017

Shares 5,196 Value ($000) $2,323 Avg Close $473.21 Range $424.12 - $523.22

Q2 2017

Shares 5,307 Value ($000) $2,606 Avg Close $435.19 Range $358.01 - $540.55

Q1 2017

Shares 5,517 Value ($000) $2,138 Avg Close $368.62 Range $338.21 - $399.00

Q4 2016

Shares 6,571 Value ($000) $2,412 Avg Close $378.17 Range $323.56 - $450.46

Q3 2016

Shares 6,275 Value ($000) $2,523 Avg Close $398.92 Range $346.51 - $441.54

Q2 2016

Shares 6,313 Value ($000) $2,205 Avg Close $383.00 Range $327.27 - $431.54

Q1 2016

Shares 6,336 Value ($000) $2,284 Avg Close $409.79 Range $347.04 - $529.97

Q4 2015

Shares 8,912 Value ($000) $4,838 Avg Close $538.82 Range $445.63 - $589.32

Q3 2015

Shares 8,829 Value ($000) $4,107 Avg Close $534.07 Range $433.12 - $602.59

Q2 2015

Shares 9,056 Value ($000) $4,620 Avg Close $485.93 Range $431.08 - $541.00

Q1 2015

Shares 9,237 Value ($000) $4,170 Avg Close $421.46 Range $390.83 - $492.77

Q4 2014

Shares 9,253 Value ($000) $3,796 Avg Close $391.09 Range $318.29 - $435.23

Q3 2014

Shares 51,106 Value ($000) $18,425 Avg Close $333.32 Range $283.49 - $367.27

Q2 2014

Shares 49,316 Value ($000) $13,930 Avg Close $294.74 Range $268.01 - $318.24

Q1 2014

Shares 47,941 Value ($000) $14,396 Avg Close $306.39 Range $261.52 - $350.55

Q4 2013

Shares 47,966 Value ($000) $13,202 Avg Close $286.03 Range $256.27 - $317.74

Q3 2013

Shares 8,566 Value ($000) $2,680 Avg Close $261.58 Range $224.53 - $318.07

Q2 2013

Shares 7,296 Value ($000) $1,641 Avg Close $231.58 Range $176.14 - $282.42

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	464	$358	$678.68	$540.32 - $792.77
Q3 2025	445	$250	$564.28	$519.56 - $609.69
Q2 2025	612	$321	$556.12	$475.17 - $638.52
Q1 2025	925	$587	$684.44	$615.89 - $745.12
Q4 2024	812	$578	$834.60	$689.18 - $1055.74
Q3 2024	1,113	$1,170	$1106.73	$1002.85 - $1204.52
Q2 2024	947	$995	$964.05	$870.40 - $1075.21
Q1 2024	1,337	$1,287	$945.64	$866.58 - $992.82
Q4 2023	1,176	$1,033	$818.96	$764.95 - $894.90
Q3 2023	877	$722	$781.58	$684.72 - $842.83
Q2 2023	915	$657	$766.75	$681.03 - $832.93
Q1 2023	973	$799	$750.05	$664.32 - $830.39
Q4 2022	1,001	$722	$733.79	$690.81 - $774.70
Q3 2022	910	$627	$625.92	$560.71 - $750.51
Q2 2022	972	$575	$646.43	$535.04 - $743.30
Q1 2022	951	$664	$629.16	$589.59 - $706.29
Q4 2021	1,104	$697	$611.44	$536.21 - $670.14
Q3 2021	1,128	$683	$617.39	$551.89 - $682.83
Q2 2021	1,153	$644	$503.83	$466.78 - $566.85
Q1 2021	1,207	$571	$484.19	$438.57 - $555.83
Q4 2020	1,167	$564	$536.82	$468.18 - $616.55
Q3 2020	1,200	$672	$602.99	$537.02 - $660.97
Q2 2020	1,292	$806	$564.49	$473.82 - $642.77
Q1 2020	1,284	$627	$410.21	$326.32 - $515.14
Q4 2019	1,006	$378	$334.59	$270.76 - $380.14
Q3 2019	1,231	$341	$294.28	$269.87 - $318.99
Q2 2019	3,342	$1,046	$331.08	$293.64 - $413.60
Q1 2019	3,571	$1,466	$409.51	$363.99 - $439.56
Q4 2018	3,345	$1,249	$364.00	$325.77 - $407.74
Q3 2018	3,322	$1,342	$378.49	$340.69 - $414.19
Q2 2018	3,370	$1,163	$311.03	$280.34 - $347.31
Q1 2018	4,519	$1,556	$345.90	$311.80 - $394.59
Q4 2017	4,857	$1,826	$402.77	$351.19 - $474.37
Q3 2017	5,196	$2,323	$473.21	$424.12 - $523.22
Q2 2017	5,307	$2,606	$435.19	$358.01 - $540.55
Q1 2017	5,517	$2,138	$368.62	$338.21 - $399.00
Q4 2016	6,571	$2,412	$378.17	$323.56 - $450.46
Q3 2016	6,275	$2,523	$398.92	$346.51 - $441.54
Q2 2016	6,313	$2,205	$383.00	$327.27 - $431.54
Q1 2016	6,336	$2,284	$409.79	$347.04 - $529.97
Q4 2015	8,912	$4,838	$538.82	$445.63 - $589.32
Q3 2015	8,829	$4,107	$534.07	$433.12 - $602.59
Q2 2015	9,056	$4,620	$485.93	$431.08 - $541.00
Q1 2015	9,237	$4,170	$421.46	$390.83 - $492.77
Q4 2014	9,253	$3,796	$391.09	$318.29 - $435.23
Q3 2014	51,106	$18,425	$333.32	$283.49 - $367.27
Q2 2014	49,316	$13,930	$294.74	$268.01 - $318.24
Q1 2014	47,941	$14,396	$306.39	$261.52 - $350.55
Q4 2013	47,966	$13,202	$286.03	$256.27 - $317.74
Q3 2013	8,566	$2,680	$261.58	$224.53 - $318.07
Q2 2013	7,296	$1,641	$231.58	$176.14 - $282.42