REGENERON PHARMACEUTICALS

Ticker: REGN CUSIP: 75886F107 Class: COM

MARSHALL WACE, LLP's Holding History (CIK: 0001318757)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 478,551 Value ($000) $369,379 Avg Close $678.68 Range $540.32 - $792.77

Q3 2025

Shares 386,884 Value ($000) $217,533 Avg Close $564.28 Range $519.56 - $609.69

Q2 2025

Shares 239,909 Value ($000) $125,952 Avg Close $556.12 Range $475.17 - $638.52

Q1 2025

Shares 1,400 Value ($000) $888 Avg Close $684.44 Range $615.89 - $745.12

Q4 2024

Shares 127,400 Value ($000) $90,751 Avg Close $834.60 Range $689.18 - $1055.74

Q3 2024

Shares 134,004 Value ($000) $140,870 Avg Close $1106.73 Range $1002.85 - $1204.52

Q2 2024

Shares 58,873 Value ($000) $61,877 Avg Close $964.05 Range $870.40 - $1075.21

Q1 2024

Shares 200,387 Value ($000) $192,870 Avg Close $945.64 Range $866.58 - $992.82

Q4 2023

Shares 94,526 Value ($000) $83,021 Avg Close $818.96 Range $764.95 - $894.90

Q3 2023

Shares 105,277 Value ($000) $86,639 Avg Close $781.58 Range $684.72 - $842.83

Q2 2023

Shares 143,508 Value ($000) $103,116 Avg Close $766.75 Range $681.03 - $832.93

Q1 2023

Shares 90,798 Value ($000) $74,606 Avg Close $750.05 Range $664.32 - $830.39

Q4 2022

Shares 9,700 Value ($000) $6,998 Avg Close $733.79 Range $690.81 - $774.70

Q3 2022

Shares 4,105 Value ($000) $2,828 Avg Close $625.92 Range $560.71 - $750.51

Q2 2022

Shares 52,055 Value ($000) $30,769 Avg Close $646.43 Range $535.04 - $743.30

Q1 2022

Shares 3,867 Value ($000) $2,701 Avg Close $629.16 Range $589.59 - $706.29

Q4 2021

Shares 129,028 Value ($000) $81,482 Avg Close $611.44 Range $536.21 - $670.14

Q3 2021

Shares 103,972 Value ($000) $62,922 Avg Close $617.39 Range $551.89 - $682.83

Q2 2021

Shares 72,452 Value ($000) $40,467 Avg Close $503.83 Range $466.78 - $566.85

Q1 2021

Shares 18,068 Value ($000) $8,548 Avg Close $484.19 Range $438.57 - $555.83

Q4 2020

Shares 2,620 Value ($000) $1,266 Avg Close $536.82 Range $468.18 - $616.55

Q2 2020

Shares 13,270 Value ($000) $8,277 Avg Close $564.49 Range $473.82 - $642.77

Q4 2019

Shares 26,276 Value ($000) $9,866 Avg Close $334.59 Range $270.76 - $380.14

Q3 2019

Shares 8,815 Value ($000) $2,446 Avg Close $294.28 Range $269.87 - $318.99

Q2 2019

Shares 121,175 Value ($000) $37,928 Avg Close $331.08 Range $293.64 - $413.60

Q4 2018

Shares 1,303 Value ($000) $487 Avg Close $364.00 Range $325.77 - $407.74

Q2 2018

Shares 8,703 Value ($000) $3,002 Avg Close $311.03 Range $280.34 - $347.31

Q4 2016

Shares 26,755 Value ($000) $9,822 Avg Close $378.17 Range $323.56 - $450.46

Q3 2016

Shares 9,639 Value ($000) $3,875 Avg Close $398.92 Range $346.51 - $441.54

Q2 2016

Shares 20,895 Value ($000) $7,297 Avg Close $383.00 Range $327.27 - $431.54

Q1 2016

Shares 13,220 Value ($000) $4,765 Avg Close $409.79 Range $347.04 - $529.97

Q4 2015

Shares 594 Value ($000) $322 Avg Close $538.82 Range $445.63 - $589.32

Q3 2015

Shares 15,122 Value ($000) $7,034 Avg Close $534.07 Range $433.12 - $602.59

Q1 2015

Shares 647 Value ($000) $292 Avg Close $421.46 Range $390.83 - $492.77

Q3 2014

Shares 36,583 Value ($000) $13,189 Avg Close $333.32 Range $283.49 - $367.27

Q2 2014

Shares 14,837 Value ($000) $4,191 Avg Close $294.74 Range $268.01 - $318.24

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	478,551	$369,379	$678.68	$540.32 - $792.77
Q3 2025	386,884	$217,533	$564.28	$519.56 - $609.69
Q2 2025	239,909	$125,952	$556.12	$475.17 - $638.52
Q1 2025	1,400	$888	$684.44	$615.89 - $745.12
Q4 2024	127,400	$90,751	$834.60	$689.18 - $1055.74
Q3 2024	134,004	$140,870	$1106.73	$1002.85 - $1204.52
Q2 2024	58,873	$61,877	$964.05	$870.40 - $1075.21
Q1 2024	200,387	$192,870	$945.64	$866.58 - $992.82
Q4 2023	94,526	$83,021	$818.96	$764.95 - $894.90
Q3 2023	105,277	$86,639	$781.58	$684.72 - $842.83
Q2 2023	143,508	$103,116	$766.75	$681.03 - $832.93
Q1 2023	90,798	$74,606	$750.05	$664.32 - $830.39
Q4 2022	9,700	$6,998	$733.79	$690.81 - $774.70
Q3 2022	4,105	$2,828	$625.92	$560.71 - $750.51
Q2 2022	52,055	$30,769	$646.43	$535.04 - $743.30
Q1 2022	3,867	$2,701	$629.16	$589.59 - $706.29
Q4 2021	129,028	$81,482	$611.44	$536.21 - $670.14
Q3 2021	103,972	$62,922	$617.39	$551.89 - $682.83
Q2 2021	72,452	$40,467	$503.83	$466.78 - $566.85
Q1 2021	18,068	$8,548	$484.19	$438.57 - $555.83
Q4 2020	2,620	$1,266	$536.82	$468.18 - $616.55
Q2 2020	13,270	$8,277	$564.49	$473.82 - $642.77
Q4 2019	26,276	$9,866	$334.59	$270.76 - $380.14
Q3 2019	8,815	$2,446	$294.28	$269.87 - $318.99
Q2 2019	121,175	$37,928	$331.08	$293.64 - $413.60
Q4 2018	1,303	$487	$364.00	$325.77 - $407.74
Q2 2018	8,703	$3,002	$311.03	$280.34 - $347.31
Q4 2016	26,755	$9,822	$378.17	$323.56 - $450.46
Q3 2016	9,639	$3,875	$398.92	$346.51 - $441.54
Q2 2016	20,895	$7,297	$383.00	$327.27 - $431.54
Q1 2016	13,220	$4,765	$409.79	$347.04 - $529.97
Q4 2015	594	$322	$538.82	$445.63 - $589.32
Q3 2015	15,122	$7,034	$534.07	$433.12 - $602.59
Q1 2015	647	$292	$421.46	$390.83 - $492.77
Q3 2014	36,583	$13,189	$333.32	$283.49 - $367.27
Q2 2014	14,837	$4,191	$294.74	$268.01 - $318.24