REGENERON PHARMACEUTICALS

Ticker: REGN CUSIP: 75886F107 Class: COM

Zurcher Kantonalbank (Zurich Cantonalbank)'s Holding History (CIK: 0001368163)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 81,242 Value ($000) $62,708 Avg Close $678.68 Range $540.32 - $792.77

Q3 2025

Shares 98,843 Value ($000) $55,576 Avg Close $564.28 Range $519.56 - $609.69

Q2 2025

Shares 105,222 Value ($000) $55,242 Avg Close $556.12 Range $475.17 - $638.52

Q1 2025

Shares 97,368 Value ($000) $61,754 Avg Close $684.44 Range $615.89 - $745.12

Q4 2024

Shares 139,958 Value ($000) $99,696 Avg Close $834.60 Range $689.18 - $1055.74

Q3 2024

Shares 139,749 Value ($000) $146,910 Avg Close $1106.73 Range $1002.85 - $1204.52

Q2 2024

Shares 144,865 Value ($000) $152,257 Avg Close $964.05 Range $870.40 - $1075.21

Q1 2024

Shares 77,630 Value ($000) $74,718 Avg Close $945.64 Range $866.58 - $992.82

Q4 2023

Shares 65,960 Value ($000) $57,932 Avg Close $818.96 Range $764.95 - $894.90

Q3 2023

Shares 65,408 Value ($000) $53,828 Avg Close $781.58 Range $684.72 - $842.83

Q2 2023

Shares 62,981 Value ($000) $45,254 Avg Close $766.75 Range $681.03 - $832.93

Q1 2023

Shares 59,990 Value ($000) $49,292 Avg Close $750.05 Range $664.32 - $830.39

Q4 2022

Shares 41,215 Value ($000) $29,736 Avg Close $733.79 Range $690.81 - $774.70

Q3 2022

Shares 33,993 Value ($000) $23,417 Avg Close $625.92 Range $560.71 - $750.51

Q2 2022

Shares 33,449 Value ($000) $19,773 Avg Close $646.43 Range $535.04 - $743.30

Q1 2022

Shares 41,413 Value ($000) $28,924 Avg Close $629.16 Range $589.59 - $706.29

Q4 2021

Shares 34,350 Value ($000) $21,693 Avg Close $611.44 Range $536.21 - $670.14

Q3 2021

Shares 50,353 Value ($000) $30,473 Avg Close $617.39 Range $551.89 - $682.83

Q2 2021

Shares 60,587 Value ($000) $33,840 Avg Close $503.83 Range $466.78 - $566.85

Q1 2021

Shares 52,454 Value ($000) $24,818 Avg Close $484.19 Range $438.57 - $555.83

Q4 2020

Shares 46,304 Value ($000) $22,370 Avg Close $536.82 Range $468.18 - $616.55

Q3 2020

Shares 37,653 Value ($000) $21,077 Avg Close $602.99 Range $537.02 - $660.97

Q2 2020

Shares 32,828 Value ($000) $20,473 Avg Close $564.49 Range $473.82 - $642.77

Q1 2020

Shares 38,120 Value ($000) $18,614 Avg Close $410.21 Range $326.32 - $515.14

Q4 2019

Shares 20,128 Value ($000) $7,558 Avg Close $334.59 Range $270.76 - $380.14

Q3 2019

Shares 19,551 Value ($000) $5,423 Avg Close $294.28 Range $269.87 - $318.99

Q2 2019

Shares 19,297 Value ($000) $6,040 Avg Close $331.08 Range $293.64 - $413.60

Q1 2019

Shares 21,055 Value ($000) $8,646 Avg Close $409.51 Range $363.99 - $439.56

Q4 2018

Shares 18,357 Value ($000) $6,856 Avg Close $364.00 Range $325.77 - $407.74

Q3 2018

Shares 15,008 Value ($000) $6,064 Avg Close $378.49 Range $340.69 - $414.19

Q2 2018

Shares 15,467 Value ($000) $5,336 Avg Close $311.03 Range $280.34 - $347.31

Q1 2018

Shares 14,837 Value ($000) $5,109 Avg Close $345.90 Range $311.80 - $394.59

Q4 2017

Shares 14,837 Value ($000) $5,578 Avg Close $402.77 Range $351.19 - $474.37

Q3 2017

Shares 17,954 Value ($000) $8,028 Avg Close $473.21 Range $424.12 - $523.22

Q2 2017

Shares 16,358 Value ($000) $8,034 Avg Close $435.19 Range $358.01 - $540.55

Q1 2017

Shares 17,656 Value ($000) $6,842 Avg Close $368.62 Range $338.21 - $399.00

Q4 2016

Shares 19,322 Value ($000) $7,093 Avg Close $378.17 Range $323.56 - $450.46

Q3 2016

Shares 16,501 Value ($000) $6,634 Avg Close $398.92 Range $346.51 - $441.54

Q2 2016

Shares 7,605 Value ($000) $2,656 Avg Close $383.00 Range $327.27 - $431.54

Q1 2016

Shares 7,105 Value ($000) $2,561 Avg Close $409.79 Range $347.04 - $529.97

Q4 2015

Shares 6,864 Value ($000) $3,726 Avg Close $538.82 Range $445.63 - $589.32

Q3 2015

Shares 8,018 Value ($000) $3,729 Avg Close $534.07 Range $433.12 - $602.59

Q2 2015

Shares 7,450 Value ($000) $3,800 Avg Close $485.93 Range $431.08 - $541.00

Q1 2015

Shares 5,120 Value ($000) $2,312 Avg Close $421.46 Range $390.83 - $492.77

Q4 2014

Shares 4,892 Value ($000) $2,007 Avg Close $391.09 Range $318.29 - $435.23

Q3 2014

Shares 5,330 Value ($000) $1,922 Avg Close $333.32 Range $283.49 - $367.27

Q2 2014

Shares 40,431 Value ($000) $11,420 Avg Close $294.74 Range $268.01 - $318.24

Q1 2014

Shares 32,700 Value ($000) $9,819 Avg Close $306.39 Range $261.52 - $350.55

Q4 2013

Shares 35,076 Value ($000) $9,654 Avg Close $286.03 Range $256.27 - $317.74

Q3 2013

Shares 36,246 Value ($000) $11,340 Avg Close $261.58 Range $224.53 - $318.07

Q2 2013

Shares 61,659 Value ($000) $13,866 Avg Close $231.58 Range $176.14 - $282.42

Q1 2013

Shares 57,459 Value ($000) $10,136 Avg Close $170.72 Range $153.31 - $184.76

Q4 2012

Shares 52,084 Value ($000) $8,910 Avg Close — Range —

Q3 2012

Shares 52,457 Value ($000) $8,008 Avg Close — Range —

Q2 2012

Shares 52,268 Value ($000) $5,970 Avg Close — Range —

Q1 2012

Shares 60,000 Value ($000) $6,997 Avg Close — Range —

Q4 2011

Shares 70,000 Value ($000) $3,880 Avg Close — Range —

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	81,242	$62,708	$678.68	$540.32 - $792.77
Q3 2025	98,843	$55,576	$564.28	$519.56 - $609.69
Q2 2025	105,222	$55,242	$556.12	$475.17 - $638.52
Q1 2025	97,368	$61,754	$684.44	$615.89 - $745.12
Q4 2024	139,958	$99,696	$834.60	$689.18 - $1055.74
Q3 2024	139,749	$146,910	$1106.73	$1002.85 - $1204.52
Q2 2024	144,865	$152,257	$964.05	$870.40 - $1075.21
Q1 2024	77,630	$74,718	$945.64	$866.58 - $992.82
Q4 2023	65,960	$57,932	$818.96	$764.95 - $894.90
Q3 2023	65,408	$53,828	$781.58	$684.72 - $842.83
Q2 2023	62,981	$45,254	$766.75	$681.03 - $832.93
Q1 2023	59,990	$49,292	$750.05	$664.32 - $830.39
Q4 2022	41,215	$29,736	$733.79	$690.81 - $774.70
Q3 2022	33,993	$23,417	$625.92	$560.71 - $750.51
Q2 2022	33,449	$19,773	$646.43	$535.04 - $743.30
Q1 2022	41,413	$28,924	$629.16	$589.59 - $706.29
Q4 2021	34,350	$21,693	$611.44	$536.21 - $670.14
Q3 2021	50,353	$30,473	$617.39	$551.89 - $682.83
Q2 2021	60,587	$33,840	$503.83	$466.78 - $566.85
Q1 2021	52,454	$24,818	$484.19	$438.57 - $555.83
Q4 2020	46,304	$22,370	$536.82	$468.18 - $616.55
Q3 2020	37,653	$21,077	$602.99	$537.02 - $660.97
Q2 2020	32,828	$20,473	$564.49	$473.82 - $642.77
Q1 2020	38,120	$18,614	$410.21	$326.32 - $515.14
Q4 2019	20,128	$7,558	$334.59	$270.76 - $380.14
Q3 2019	19,551	$5,423	$294.28	$269.87 - $318.99
Q2 2019	19,297	$6,040	$331.08	$293.64 - $413.60
Q1 2019	21,055	$8,646	$409.51	$363.99 - $439.56
Q4 2018	18,357	$6,856	$364.00	$325.77 - $407.74
Q3 2018	15,008	$6,064	$378.49	$340.69 - $414.19
Q2 2018	15,467	$5,336	$311.03	$280.34 - $347.31
Q1 2018	14,837	$5,109	$345.90	$311.80 - $394.59
Q4 2017	14,837	$5,578	$402.77	$351.19 - $474.37
Q3 2017	17,954	$8,028	$473.21	$424.12 - $523.22
Q2 2017	16,358	$8,034	$435.19	$358.01 - $540.55
Q1 2017	17,656	$6,842	$368.62	$338.21 - $399.00
Q4 2016	19,322	$7,093	$378.17	$323.56 - $450.46
Q3 2016	16,501	$6,634	$398.92	$346.51 - $441.54
Q2 2016	7,605	$2,656	$383.00	$327.27 - $431.54
Q1 2016	7,105	$2,561	$409.79	$347.04 - $529.97
Q4 2015	6,864	$3,726	$538.82	$445.63 - $589.32
Q3 2015	8,018	$3,729	$534.07	$433.12 - $602.59
Q2 2015	7,450	$3,800	$485.93	$431.08 - $541.00
Q1 2015	5,120	$2,312	$421.46	$390.83 - $492.77
Q4 2014	4,892	$2,007	$391.09	$318.29 - $435.23
Q3 2014	5,330	$1,922	$333.32	$283.49 - $367.27
Q2 2014	40,431	$11,420	$294.74	$268.01 - $318.24
Q1 2014	32,700	$9,819	$306.39	$261.52 - $350.55
Q4 2013	35,076	$9,654	$286.03	$256.27 - $317.74
Q3 2013	36,246	$11,340	$261.58	$224.53 - $318.07
Q2 2013	61,659	$13,866	$231.58	$176.14 - $282.42
Q1 2013	57,459	$10,136	$170.72	$153.31 - $184.76
Q4 2012	52,084	$8,910	—	—
Q3 2012	52,457	$8,008	—	—
Q2 2012	52,268	$5,970	—	—
Q1 2012	60,000	$6,997	—	—
Q4 2011	70,000	$3,880	—	—