REGENERON PHARMACEUTICALS

Ticker: REGN CUSIP: 75886F107 Class: COM

Holocene Advisors, LP's Holding History (CIK: 0001700574)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 460,723 Value ($000) $355,618 Avg Close $678.68 Range $540.32 - $792.77

Q3 2025

Shares 151,733 Value ($000) $85,315 Avg Close $564.28 Range $519.56 - $609.69

Q1 2024

Shares 81,857 Value ($000) $78,787 Avg Close $945.64 Range $866.58 - $992.82

Q4 2023

Shares 360,480 Value ($000) $316,606 Avg Close $818.96 Range $764.95 - $894.90

Q3 2023

Shares 177,753 Value ($000) $146,284 Avg Close $781.58 Range $684.72 - $842.83

Q2 2023

Shares 160,862 Value ($000) $115,586 Avg Close $766.75 Range $681.03 - $832.93

Q1 2023

Shares 128,249 Value ($000) $105,378 Avg Close $750.05 Range $664.32 - $830.39

Q4 2022

Shares 72,176 Value ($000) $52,074 Avg Close $733.79 Range $690.81 - $774.70

Q4 2020

Shares 1,498 Value ($000) $724 Avg Close $536.82 Range $468.18 - $616.55

Q2 2020

Shares 122,952 Value ($000) $76,679 Avg Close $564.49 Range $473.82 - $642.77

Q1 2018

Shares 752 Value ($000) $259 Avg Close $345.90 Range $311.80 - $394.59

Q4 2017

Shares 2,365 Value ($000) $889 Avg Close $402.77 Range $351.19 - $474.37

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	460,723	$355,618	$678.68	$540.32 - $792.77
Q3 2025	151,733	$85,315	$564.28	$519.56 - $609.69
Q1 2024	81,857	$78,787	$945.64	$866.58 - $992.82
Q4 2023	360,480	$316,606	$818.96	$764.95 - $894.90
Q3 2023	177,753	$146,284	$781.58	$684.72 - $842.83
Q2 2023	160,862	$115,586	$766.75	$681.03 - $832.93
Q1 2023	128,249	$105,378	$750.05	$664.32 - $830.39
Q4 2022	72,176	$52,074	$733.79	$690.81 - $774.70
Q4 2020	1,498	$724	$536.82	$468.18 - $616.55
Q2 2020	122,952	$76,679	$564.49	$473.82 - $642.77
Q1 2018	752	$259	$345.90	$311.80 - $394.59
Q4 2017	2,365	$889	$402.77	$351.19 - $474.37