REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

STATE STREET CORP's Holding History (CIK: 0000093751)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 23,941 Value ($000) $5 Avg Close — Range —
Q2 2018
Shares 26,075 Value ($000) $16 Avg Close — Range —
Q1 2018
Shares 56,779 Value ($000) $39 Avg Close — Range —
Q4 2017
Shares 47,869 Value ($000) $51 Avg Close — Range —
Q3 2017
Shares 26,000 Value ($000) $34 Avg Close — Range —
Q2 2017
Shares 32,500 Value ($000) $32 Avg Close — Range —
Q1 2017
Shares 580,549 Value ($000) $959 Avg Close — Range —
Q4 2016
Shares 551,941 Value ($000) $1,240 Avg Close — Range —
Q3 2016
Shares 562,328 Value ($000) $1,856 Avg Close — Range —
Q2 2016
Shares 551,539 Value ($000) $1,592 Avg Close — Range —
Q1 2016
Shares 377,896 Value ($000) $2,618 Avg Close — Range —
Q4 2015
Shares 344,677 Value ($000) $3,006 Avg Close — Range —
Q3 2015
Shares 324,565 Value ($000) $2,120 Avg Close — Range —
Q2 2015
Shares 2,659,285 Value ($000) $29,145 Avg Close — Range —
Q1 2015
Shares 1,358,746 Value ($000) $23,016 Avg Close — Range —
Q4 2014
Shares 1,219,814 Value ($000) $19,566 Avg Close — Range —
Q3 2014
Shares 126,337 Value ($000) $863 Avg Close — Range —
Q2 2014
Shares 113,341 Value ($000) $910 Avg Close — Range —
Q1 2014
Shares 121,839 Value ($000) $1,098 Avg Close — Range —
Q4 2013
Shares 132,298 Value ($000) $978 Avg Close — Range —
Q3 2013
Shares 139,636 Value ($000) $1,316 Avg Close — Range —
Q2 2013
Shares 144,627 Value ($000) $1,421 Avg Close — Range —