REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

TOCQUEVILLE ASSET MANAGEMENT L.P.'s Holding History (CIK: 0000883961)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 113,250 Value ($000) $374 Avg Close — Range —
Q2 2016
Shares 114,150 Value ($000) $330 Avg Close — Range —
Q1 2016
Shares 133,450 Value ($000) $925 Avg Close — Range —
Q4 2015
Shares 137,250 Value ($000) $1,197 Avg Close — Range —
Q3 2015
Shares 140,950 Value ($000) $922 Avg Close — Range —
Q2 2015
Shares 44,700 Value ($000) $490 Avg Close — Range —
Q1 2015
Shares 27,900 Value ($000) $473 Avg Close — Range —
Q4 2014
Shares 39,600 Value ($000) $635 Avg Close — Range —
Q2 2014
Shares 68,500 Value ($000) $551 Avg Close — Range —
Q1 2014
Shares 64,000 Value ($000) $577 Avg Close — Range —
Q4 2013
Shares 36,000 Value ($000) $266 Avg Close — Range —
Q3 2013
Shares 31,000 Value ($000) $292 Avg Close — Range —