REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

WELLINGTON MANAGEMENT GROUP LLP's Holding History (CIK: 0000902219)

Note: Option positions (PUT/CALL) are excluded.

Q4 2016
Shares 4,683,489 Value ($000) $10,538 Avg Close — Range —
Q3 2016
Shares 4,648,815 Value ($000) $15,341 Avg Close — Range —
Q2 2016
Shares 4,886,125 Value ($000) $14,121 Avg Close — Range —
Q1 2016
Shares 4,031,571 Value ($000) $27,938 Avg Close — Range —
Q4 2015
Shares 4,213,856 Value ($000) $36,745 Avg Close — Range —
Q3 2015
Shares 4,217,986 Value ($000) $27,586 Avg Close — Range —
Q2 2015
Shares 4,853,442 Value ($000) $53,194 Avg Close — Range —
Q1 2015
Shares 5,410,597 Value ($000) $91,656 Avg Close — Range —
Q4 2014
Shares 3,779,174 Value ($000) $60,618 Avg Close — Range —
Q3 2014
Shares 1,050,980 Value ($000) $7,179 Avg Close — Range —
Q2 2014
Shares 940,070 Value ($000) $7,558 Avg Close — Range —
Q1 2014
Shares 744,960 Value ($000) $6,719 Avg Close — Range —
Q4 2013
Shares 804,700 Value ($000) $5,947 Avg Close — Range —