REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM's Holding History (CIK: 0001081019)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 79,643 Value ($000) $131 Avg Close — Range —
Q4 2016
Shares 79,843 Value ($000) $180 Avg Close — Range —
Q3 2016
Shares 82,143 Value ($000) $271 Avg Close — Range —
Q2 2016
Shares 81,343 Value ($000) $235 Avg Close — Range —
Q1 2016
Shares 59,890 Value ($000) $415 Avg Close — Range —
Q4 2015
Shares 52,450 Value ($000) $457 Avg Close — Range —
Q3 2015
Shares 51,464 Value ($000) $337 Avg Close — Range —
Q2 2015
Shares 51,664 Value ($000) $566 Avg Close — Range —
Q1 2015
Shares 28,125 Value ($000) $476 Avg Close — Range —
Q4 2014
Shares 28,625 Value ($000) $459 Avg Close — Range —
Q3 2014
Shares 25,217 Value ($000) $172 Avg Close — Range —
Q2 2014
Shares 25,073 Value ($000) $202 Avg Close — Range —
Q1 2014
Shares 18,273 Value ($000) $165 Avg Close — Range —
Q4 2013
Shares 18,273 Value ($000) $135 Avg Close — Range —
Q3 2013
Shares 18,273 Value ($000) $172 Avg Close — Range —
Q2 2013
Shares 15,573 Value ($000) $153 Avg Close — Range —
Q1 2013
Shares 22,500 Value ($000) $174 Avg Close — Range —