REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

SCHRODER INVESTMENT MANAGEMENT GROUP's Holding History (CIK: 0001086619)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 109,987 Value ($000) $363 Avg Close — Range —
Q2 2016
Shares 109,987 Value ($000) $318 Avg Close — Range —
Q1 2016
Shares 109,987 Value ($000) $720 Avg Close — Range —
Q4 2015
Shares 37,498 Value ($000) $327 Avg Close — Range —
Q3 2015
Shares 37,498 Value ($000) $245 Avg Close — Range —
Q2 2015
Shares 37,498 Value ($000) $379 Avg Close — Range —
Q1 2015
Shares 37,498 Value ($000) $631 Avg Close — Range —
Q4 2014
Shares 66,594 Value ($000) $1,068 Avg Close — Range —
Q3 2014
Shares 142,668 Value ($000) $974,423 Avg Close — Range —