REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

EVENTIDE ASSET MANAGEMENT, LLC's Holding History (CIK: 0001442891)

Note: Option positions (PUT/CALL) are excluded.

Q4 2015
Shares 160,600 Value ($000) $1,400 Avg Close — Range —
Q3 2015
Shares 160,516 Value ($000) $1,050 Avg Close — Range —
Q2 2015
Shares 160,516 Value ($000) $1,759 Avg Close — Range —
Q1 2015
Shares 116,000 Value ($000) $1,965 Avg Close — Range —
Q4 2014
Shares 60,000 Value ($000) $962 Avg Close — Range —