REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

DekaBank Deutsche Girozentrale's Holding History (CIK: 0001456228)

Note: Option positions (PUT/CALL) are excluded.

Q1 2016
Shares 24,500 Value ($000) $160 Avg Close — Range —
Q4 2015
Shares 26,300 Value ($000) $242 Avg Close — Range —
Q3 2015
Shares 25,800 Value ($000) $169 Avg Close — Range —
Q2 2015
Shares 24,800 Value ($000) $272 Avg Close — Range —
Q1 2015
Shares 23,700 Value ($000) $401 Avg Close — Range —
Q4 2014
Shares 25,600 Value ($000) $411 Avg Close — Range —
Q3 2014
Shares 25,500 Value ($000) $174 Avg Close — Range —
Q2 2014
Shares 25,000 Value ($000) $201 Avg Close — Range —
Q1 2014
Shares 25,500 Value ($000) $230 Avg Close — Range —