REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

Candriam S.C.A.'s Holding History (CIK: 0001537014)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018
Shares 500,000 Value ($000) $330 Avg Close — Range —
Q1 2018
Shares 500,000 Value ($000) $359 Avg Close — Range —
Q4 2017
Shares 500,000 Value ($000) $520 Avg Close — Range —
Q3 2017
Shares 600,000 Value ($000) $750 Avg Close — Range —
Q1 2015
Shares 38,000 Value ($000) $644 Avg Close — Range —
Q4 2014
Shares 200,000 Value ($000) $3,208 Avg Close — Range —