REGULUS THERAPEUTICS INC

CUSIP: 75915K101 Class: COM

Swiss National Bank's Holding History (CIK: 0001582202)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 58,200 Value ($000) $192 Avg Close — Range —
Q2 2016
Shares 58,200 Value ($000) $168 Avg Close — Range —
Q1 2016
Shares 53,300 Value ($000) $358 Avg Close — Range —
Q4 2015
Shares 44,000 Value ($000) $384 Avg Close — Range —
Q3 2015
Shares 44,000 Value ($000) $288 Avg Close — Range —
Q2 2015
Shares 39,000 Value ($000) $427 Avg Close — Range —