REGULUS THERAPEUTICS INC

CUSIP: 75915K200 Class: COM

TWO SIGMA SECURITIES, LLC's Holding History (CIK: 0001450144)

Note: Option positions (PUT/CALL) are excluded.

Q2 2021
Shares 37,741 Value ($000) $31 Avg Close — Range —
Q3 2020
Shares 16,659 Value ($000) $9 Avg Close — Range —
Q2 2020
Shares 11,910 Value ($000) $8 Avg Close — Range —