REGULUS THERAPEUTICS INC

CUSIP: 75915K309 Class: Common Stock

TWO SIGMA INVESTMENTS, LP's Holding History (CIK: 0001179392)

Note: Option positions (PUT/CALL) are excluded.

Q4 2024
Shares 22,264 Value ($000) $35 Avg Close — Range —
Q3 2024
Shares 19,181 Value ($000) $30 Avg Close — Range —
Q2 2024
Shares 35,299 Value ($000) $63 Avg Close — Range —