REPLIGEN CORP

Ticker: RGEN CUSIP: 759916109 Class: Common Stock

FMR LLC's Holding History (CIK: 0000315066)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 2,867,846 Value ($000) $469,925 Avg Close $156.63 Range $134.19 - $174.01

Q3 2025

Shares 2,691,212 Value ($000) $359,734 Avg Close $121.47 Range $110.77 - $135.57

Q2 2025

Shares 1,613,304 Value ($000) $200,663 Avg Close $127.25 Range $102.97 - $148.94

Q1 2025

Shares 732,404 Value ($000) $93,191 Avg Close $153.93 Range $125.39 - $182.52

Q4 2024

Shares 754,392 Value ($000) $108,587 Avg Close $143.40 Range $121.52 - $161.24

Q3 2024

Shares 803,269 Value ($000) $119,542 Avg Close $143.39 Range $117.63 - $172.65

Q2 2024

Shares 1,444,788 Value ($000) $182,130 Avg Close $156.74 Range $113.50 - $184.98

Q1 2024

Shares 2,257,789 Value ($000) $415,253 Avg Close $190.44 Range $167.40 - $211.13

Q4 2023

Shares 1,882,516 Value ($000) $338,476 Avg Close $155.67 Range $110.45 - $188.31

Q3 2023

Shares 2,223,761 Value ($000) $353,600 Avg Close $163.47 Range $134.64 - $181.26

Q2 2023

Shares 2,466,191 Value ($000) $348,867 Avg Close $160.35 Range $135.37 - $182.42

Q1 2023

Shares 2,016,644 Value ($000) $339,522 Avg Close $178.42 Range $147.53 - $200.98

Q4 2022

Shares 1,003,264 Value ($000) $169,863 Avg Close $181.39 Range $158.58 - $225.62

Q3 2022

Shares 157,745 Value ($000) $29,515 Avg Close $210.87 Range $157.33 - $262.26

Q2 2022

Shares 2,856 Value ($000) $464 Avg Close $158.16 Range $137.21 - $190.59

Q1 2022

Shares 385,765 Value ($000) $72,559 Avg Close $189.96 Range $156.28 - $265.78

Q4 2021

Shares 382,077 Value ($000) $101,188 Avg Close $269.41 Range $243.29 - $306.98

Q3 2021

Shares 384,343 Value ($000) $111,072 Avg Close $256.54 Range $193.03 - $327.32

Q2 2021

Shares 385,303 Value ($000) $76,914 Avg Close $193.99 Range $162.29 - $223.03

Q1 2021

Shares 478,073 Value ($000) $92,943 Avg Close $205.03 Range $173.09 - $228.84

Q4 2020

Shares 474,672 Value ($000) $90,962 Avg Close $181.94 Range $146.52 - $212.55

Q3 2020

Shares 287,736 Value ($000) $42,452 Avg Close $142.94 Range $120.12 - $159.97

Q2 2020

Shares 244,906 Value ($000) $30,272 Avg Close $117.64 Range $92.00 - $143.93

Q1 2020

Shares 222,534 Value ($000) $21,483 Avg Close $96.54 Range $78.41 - $109.94

Q4 2019

Shares 140,275 Value ($000) $12,975 Avg Close $84.01 Range $72.32 - $93.50

Q3 2019

Shares 405,193 Value ($000) $31,074 Avg Close $87.47 Range $75.80 - $99.25

Q2 2019

Shares 434,553 Value ($000) $37,351 Avg Close $68.16 Range $52.87 - $86.16

Q1 2019

Shares 612,677 Value ($000) $36,197 Avg Close $57.51 Range $49.07 - $63.41

Q4 2018

Shares 622,213 Value ($000) $32,816 Avg Close $58.65 Range $48.26 - $70.50

Q3 2018

Shares 730,013 Value ($000) $40,487 Avg Close $51.54 Range $45.00 - $58.99

Q2 2018

Shares 907,513 Value ($000) $42,689 Avg Close $41.16 Range $34.61 - $47.87

Q1 2018

Shares 907,513 Value ($000) $32,834 Avg Close $35.17 Range $29.56 - $37.82

Q4 2017

Shares 909,355 Value ($000) $32,991 Avg Close $36.20 Range $31.96 - $40.05

Q3 2017

Shares 1,463,264 Value ($000) $56,072 Avg Close $41.91 Range $35.73 - $46.12

Q2 2017

Shares 1,334,090 Value ($000) $55,285 Avg Close $38.00 Range $32.73 - $46.81

Q1 2017

Shares 1,256,030 Value ($000) $44,212 Avg Close $31.67 Range $28.48 - $35.61

Q4 2016

Shares 1,297,960 Value ($000) $40,003 Avg Close $30.93 Range $26.16 - $34.06

Q3 2016

Shares 1,574,861 Value ($000) $47,545 Avg Close $30.18 Range $25.93 - $33.79

Q2 2016

Shares 1,523,873 Value ($000) $41,693 Avg Close $25.57 Range $21.11 - $28.97

Q1 2016

Shares 1,595,596 Value ($000) $42,794 Avg Close $24.47 Range $20.07 - $28.85

Q4 2015

Shares 2,518,868 Value ($000) $71,259 Avg Close $28.84 Range $21.69 - $36.00

Q3 2015

Shares 2,606,473 Value ($000) $72,590 Avg Close $36.14 Range $27.25 - $42.22

Q2 2015

Shares 3,657,430 Value ($000) $150,942 Avg Close $36.64 Range $28.88 - $42.48

Q1 2015

Shares 2,707,522 Value ($000) $82,200 Avg Close $25.94 Range $19.53 - $34.15

Q4 2014

Shares 2,532,805 Value ($000) $50,150 Avg Close $22.36 Range $19.02 - $26.75

Q3 2014

Shares 2,475,896 Value ($000) $49,295 Avg Close $21.05 Range $18.23 - $24.68

Q2 2014

Shares 2,392,361 Value ($000) $54,522 Avg Close $17.80 Range $12.60 - $23.14

Q1 2014

Shares 1,570,786 Value ($000) $20,200 Avg Close $14.34 Range $11.70 - $17.26

Q4 2013

Shares 948,150 Value ($000) $12,933 Avg Close $11.94 Range $9.89 - $14.05

Q3 2013

Shares 1,064,731 Value ($000) $11,808 Avg Close $9.95 Range $8.25 - $11.44

Q2 2013

Shares 1,095,131 Value ($000) $9,023 Avg Close $8.40 Range $6.65 - $9.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	2,867,846	$469,925	$156.63	$134.19 - $174.01
Q3 2025	2,691,212	$359,734	$121.47	$110.77 - $135.57
Q2 2025	1,613,304	$200,663	$127.25	$102.97 - $148.94
Q1 2025	732,404	$93,191	$153.93	$125.39 - $182.52
Q4 2024	754,392	$108,587	$143.40	$121.52 - $161.24
Q3 2024	803,269	$119,542	$143.39	$117.63 - $172.65
Q2 2024	1,444,788	$182,130	$156.74	$113.50 - $184.98
Q1 2024	2,257,789	$415,253	$190.44	$167.40 - $211.13
Q4 2023	1,882,516	$338,476	$155.67	$110.45 - $188.31
Q3 2023	2,223,761	$353,600	$163.47	$134.64 - $181.26
Q2 2023	2,466,191	$348,867	$160.35	$135.37 - $182.42
Q1 2023	2,016,644	$339,522	$178.42	$147.53 - $200.98
Q4 2022	1,003,264	$169,863	$181.39	$158.58 - $225.62
Q3 2022	157,745	$29,515	$210.87	$157.33 - $262.26
Q2 2022	2,856	$464	$158.16	$137.21 - $190.59
Q1 2022	385,765	$72,559	$189.96	$156.28 - $265.78
Q4 2021	382,077	$101,188	$269.41	$243.29 - $306.98
Q3 2021	384,343	$111,072	$256.54	$193.03 - $327.32
Q2 2021	385,303	$76,914	$193.99	$162.29 - $223.03
Q1 2021	478,073	$92,943	$205.03	$173.09 - $228.84
Q4 2020	474,672	$90,962	$181.94	$146.52 - $212.55
Q3 2020	287,736	$42,452	$142.94	$120.12 - $159.97
Q2 2020	244,906	$30,272	$117.64	$92.00 - $143.93
Q1 2020	222,534	$21,483	$96.54	$78.41 - $109.94
Q4 2019	140,275	$12,975	$84.01	$72.32 - $93.50
Q3 2019	405,193	$31,074	$87.47	$75.80 - $99.25
Q2 2019	434,553	$37,351	$68.16	$52.87 - $86.16
Q1 2019	612,677	$36,197	$57.51	$49.07 - $63.41
Q4 2018	622,213	$32,816	$58.65	$48.26 - $70.50
Q3 2018	730,013	$40,487	$51.54	$45.00 - $58.99
Q2 2018	907,513	$42,689	$41.16	$34.61 - $47.87
Q1 2018	907,513	$32,834	$35.17	$29.56 - $37.82
Q4 2017	909,355	$32,991	$36.20	$31.96 - $40.05
Q3 2017	1,463,264	$56,072	$41.91	$35.73 - $46.12
Q2 2017	1,334,090	$55,285	$38.00	$32.73 - $46.81
Q1 2017	1,256,030	$44,212	$31.67	$28.48 - $35.61
Q4 2016	1,297,960	$40,003	$30.93	$26.16 - $34.06
Q3 2016	1,574,861	$47,545	$30.18	$25.93 - $33.79
Q2 2016	1,523,873	$41,693	$25.57	$21.11 - $28.97
Q1 2016	1,595,596	$42,794	$24.47	$20.07 - $28.85
Q4 2015	2,518,868	$71,259	$28.84	$21.69 - $36.00
Q3 2015	2,606,473	$72,590	$36.14	$27.25 - $42.22
Q2 2015	3,657,430	$150,942	$36.64	$28.88 - $42.48
Q1 2015	2,707,522	$82,200	$25.94	$19.53 - $34.15
Q4 2014	2,532,805	$50,150	$22.36	$19.02 - $26.75
Q3 2014	2,475,896	$49,295	$21.05	$18.23 - $24.68
Q2 2014	2,392,361	$54,522	$17.80	$12.60 - $23.14
Q1 2014	1,570,786	$20,200	$14.34	$11.70 - $17.26
Q4 2013	948,150	$12,933	$11.94	$9.89 - $14.05
Q3 2013	1,064,731	$11,808	$9.95	$8.25 - $11.44
Q2 2013	1,095,131	$9,023	$8.40	$6.65 - $9.65