REPLIGEN CORP

Ticker: RGEN CUSIP: 759916109 Class: Common Stock

CHARLES SCHWAB INVESTMENT MANAGEMENT INC's Holding History (CIK: 0000884546)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 430,704 Value ($000) $70,575 Avg Close $156.63 Range $134.19 - $174.01

Q3 2025

Shares 422,088 Value ($000) $56,421 Avg Close $121.47 Range $110.77 - $135.57

Q2 2025

Shares 406,263 Value ($000) $50,531 Avg Close $127.25 Range $102.97 - $148.94

Q1 2025

Shares 396,150 Value ($000) $50,406 Avg Close $153.93 Range $125.39 - $182.52

Q4 2024

Shares 377,900 Value ($000) $54,395 Avg Close $143.40 Range $121.52 - $161.24

Q3 2024

Shares 363,379 Value ($000) $54,078 Avg Close $143.39 Range $117.63 - $172.65

Q2 2024

Shares 357,901 Value ($000) $45,117 Avg Close $156.74 Range $113.50 - $184.98

Q1 2024

Shares 352,211 Value ($000) $64,779 Avg Close $190.44 Range $167.40 - $211.13

Q4 2023

Shares 342,452 Value ($000) $61,573 Avg Close $155.67 Range $110.45 - $188.31

Q3 2023

Shares 326,667 Value ($000) $51,943 Avg Close $163.47 Range $134.64 - $181.26

Q2 2023

Shares 318,000 Value ($000) $44,984 Avg Close $160.35 Range $135.37 - $182.42

Q1 2023

Shares 312,258 Value ($000) $52,572 Avg Close $178.42 Range $147.53 - $200.98

Q4 2022

Shares 307,258 Value ($000) $52,022 Avg Close $181.39 Range $158.58 - $225.62

Q3 2022

Shares 294,893 Value ($000) $55,178 Avg Close $210.87 Range $157.33 - $262.26

Q2 2022

Shares 293,863 Value ($000) $47,724 Avg Close $158.16 Range $137.21 - $190.59

Q1 2022

Shares 288,185 Value ($000) $54,205 Avg Close $189.96 Range $156.28 - $265.78

Q4 2021

Shares 281,193 Value ($000) $74,471 Avg Close $269.41 Range $243.29 - $306.98

Q3 2021

Shares 273,772 Value ($000) $79,118 Avg Close $256.54 Range $193.03 - $327.32

Q2 2021

Shares 383,721 Value ($000) $76,599 Avg Close $193.99 Range $162.29 - $223.03

Q1 2021

Shares 374,477 Value ($000) $72,803 Avg Close $205.03 Range $173.09 - $228.84

Q4 2020

Shares 386,021 Value ($000) $73,974 Avg Close $181.94 Range $146.52 - $212.55

Q3 2020

Shares 388,343 Value ($000) $57,297 Avg Close $142.94 Range $120.12 - $159.97

Q2 2020

Shares 375,513 Value ($000) $46,418 Avg Close $117.64 Range $92.00 - $143.93

Q1 2020

Shares 460,905 Value ($000) $44,496 Avg Close $96.54 Range $78.41 - $109.94

Q4 2019

Shares 440,241 Value ($000) $40,723 Avg Close $84.01 Range $72.32 - $93.50

Q3 2019

Shares 432,596 Value ($000) $33,176 Avg Close $87.47 Range $75.80 - $99.25

Q2 2019

Shares 298,213 Value ($000) $25,632 Avg Close $68.16 Range $52.87 - $86.16

Q1 2019

Shares 304,103 Value ($000) $17,967 Avg Close $57.51 Range $49.07 - $63.41

Q4 2018

Shares 266,645 Value ($000) $14,063 Avg Close $58.65 Range $48.26 - $70.50

Q3 2018

Shares 214,019 Value ($000) $11,870 Avg Close $51.54 Range $45.00 - $58.99

Q2 2018

Shares 202,201 Value ($000) $9,512 Avg Close $41.16 Range $34.61 - $47.87

Q1 2018

Shares 190,417 Value ($000) $6,890 Avg Close $35.17 Range $29.56 - $37.82

Q4 2017

Shares 210,000 Value ($000) $7,619 Avg Close $36.20 Range $31.96 - $40.05

Q3 2017

Shares 224,388 Value ($000) $8,599 Avg Close $41.91 Range $35.73 - $46.12

Q2 2017

Shares 215,450 Value ($000) $8,929 Avg Close $38.00 Range $32.73 - $46.81

Q1 2017

Shares 236,201 Value ($000) $8,315 Avg Close $31.67 Range $28.48 - $35.61

Q4 2016

Shares 278,812 Value ($000) $8,593 Avg Close $30.93 Range $26.16 - $34.06

Q3 2016

Shares 267,673 Value ($000) $8,082 Avg Close $30.18 Range $25.93 - $33.79

Q2 2016

Shares 175,590 Value ($000) $4,805 Avg Close $25.57 Range $21.11 - $28.97

Q1 2016

Shares 169,080 Value ($000) $4,535 Avg Close $24.47 Range $20.07 - $28.85

Q4 2015

Shares 163,654 Value ($000) $4,630 Avg Close $28.84 Range $21.69 - $36.00

Q3 2015

Shares 148,394 Value ($000) $4,133 Avg Close $36.14 Range $27.25 - $42.22

Q2 2015

Shares 87,154 Value ($000) $3,597 Avg Close $36.64 Range $28.88 - $42.48

Q1 2015

Shares 247,998 Value ($000) $7,530 Avg Close $25.94 Range $19.53 - $34.15

Q4 2014

Shares 324,351 Value ($000) $6,423 Avg Close $22.36 Range $19.02 - $26.75

Q3 2014

Shares 328,649 Value ($000) $6,544 Avg Close $21.05 Range $18.23 - $24.68

Q2 2014

Shares 211,540 Value ($000) $4,821 Avg Close $17.80 Range $12.60 - $23.14

Q1 2014

Shares 185,380 Value ($000) $2,384 Avg Close $14.34 Range $11.70 - $17.26

Q4 2013

Shares 85,900 Value ($000) $1,172 Avg Close $11.94 Range $9.89 - $14.05

Q3 2013

Shares 85,900 Value ($000) $974 Avg Close $9.95 Range $8.25 - $11.44

Q2 2013

Shares 85,900 Value ($000) $722 Avg Close $8.40 Range $6.65 - $9.65

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	430,704	$70,575	$156.63	$134.19 - $174.01
Q3 2025	422,088	$56,421	$121.47	$110.77 - $135.57
Q2 2025	406,263	$50,531	$127.25	$102.97 - $148.94
Q1 2025	396,150	$50,406	$153.93	$125.39 - $182.52
Q4 2024	377,900	$54,395	$143.40	$121.52 - $161.24
Q3 2024	363,379	$54,078	$143.39	$117.63 - $172.65
Q2 2024	357,901	$45,117	$156.74	$113.50 - $184.98
Q1 2024	352,211	$64,779	$190.44	$167.40 - $211.13
Q4 2023	342,452	$61,573	$155.67	$110.45 - $188.31
Q3 2023	326,667	$51,943	$163.47	$134.64 - $181.26
Q2 2023	318,000	$44,984	$160.35	$135.37 - $182.42
Q1 2023	312,258	$52,572	$178.42	$147.53 - $200.98
Q4 2022	307,258	$52,022	$181.39	$158.58 - $225.62
Q3 2022	294,893	$55,178	$210.87	$157.33 - $262.26
Q2 2022	293,863	$47,724	$158.16	$137.21 - $190.59
Q1 2022	288,185	$54,205	$189.96	$156.28 - $265.78
Q4 2021	281,193	$74,471	$269.41	$243.29 - $306.98
Q3 2021	273,772	$79,118	$256.54	$193.03 - $327.32
Q2 2021	383,721	$76,599	$193.99	$162.29 - $223.03
Q1 2021	374,477	$72,803	$205.03	$173.09 - $228.84
Q4 2020	386,021	$73,974	$181.94	$146.52 - $212.55
Q3 2020	388,343	$57,297	$142.94	$120.12 - $159.97
Q2 2020	375,513	$46,418	$117.64	$92.00 - $143.93
Q1 2020	460,905	$44,496	$96.54	$78.41 - $109.94
Q4 2019	440,241	$40,723	$84.01	$72.32 - $93.50
Q3 2019	432,596	$33,176	$87.47	$75.80 - $99.25
Q2 2019	298,213	$25,632	$68.16	$52.87 - $86.16
Q1 2019	304,103	$17,967	$57.51	$49.07 - $63.41
Q4 2018	266,645	$14,063	$58.65	$48.26 - $70.50
Q3 2018	214,019	$11,870	$51.54	$45.00 - $58.99
Q2 2018	202,201	$9,512	$41.16	$34.61 - $47.87
Q1 2018	190,417	$6,890	$35.17	$29.56 - $37.82
Q4 2017	210,000	$7,619	$36.20	$31.96 - $40.05
Q3 2017	224,388	$8,599	$41.91	$35.73 - $46.12
Q2 2017	215,450	$8,929	$38.00	$32.73 - $46.81
Q1 2017	236,201	$8,315	$31.67	$28.48 - $35.61
Q4 2016	278,812	$8,593	$30.93	$26.16 - $34.06
Q3 2016	267,673	$8,082	$30.18	$25.93 - $33.79
Q2 2016	175,590	$4,805	$25.57	$21.11 - $28.97
Q1 2016	169,080	$4,535	$24.47	$20.07 - $28.85
Q4 2015	163,654	$4,630	$28.84	$21.69 - $36.00
Q3 2015	148,394	$4,133	$36.14	$27.25 - $42.22
Q2 2015	87,154	$3,597	$36.64	$28.88 - $42.48
Q1 2015	247,998	$7,530	$25.94	$19.53 - $34.15
Q4 2014	324,351	$6,423	$22.36	$19.02 - $26.75
Q3 2014	328,649	$6,544	$21.05	$18.23 - $24.68
Q2 2014	211,540	$4,821	$17.80	$12.60 - $23.14
Q1 2014	185,380	$2,384	$14.34	$11.70 - $17.26
Q4 2013	85,900	$1,172	$11.94	$9.89 - $14.05
Q3 2013	85,900	$974	$9.95	$8.25 - $11.44
Q2 2013	85,900	$722	$8.40	$6.65 - $9.65