REPLIGEN CORP

Ticker: RGEN CUSIP: 759916109 Class: Common Stock

ADAGE CAPITAL PARTNERS GP, L.L.C.'s Holding History (CIK: 0001165408)

Note: Option positions (PUT/CALL) are excluded.

Q3 2025

Shares 5,000 Value ($000) $668 Avg Close $121.47 Range $110.77 - $135.57

Q3 2024

Shares 100,000 Value ($000) $14,882 Avg Close $143.39 Range $117.63 - $172.65

Q2 2024

Shares 50,000 Value ($000) $6,303 Avg Close $156.74 Range $113.50 - $184.98

Q1 2024

Shares 115,000 Value ($000) $21,151 Avg Close $190.44 Range $167.40 - $211.13

Q4 2021

Shares 40,000 Value ($000) $10,594 Avg Close $269.41 Range $243.29 - $306.98

Period	Shares	Value ($000)	Average Close	Price Range
Q3 2025	5,000	$668	$121.47	$110.77 - $135.57
Q3 2024	100,000	$14,882	$143.39	$117.63 - $172.65
Q2 2024	50,000	$6,303	$156.74	$113.50 - $184.98
Q1 2024	115,000	$21,151	$190.44	$167.40 - $211.13
Q4 2021	40,000	$10,594	$269.41	$243.29 - $306.98