REPLIGEN CORP

Ticker: RGEN CUSIP: 759916109 Class: Common Stock

Brevan Howard Capital Management LP's Holding History (CIK: 0001512857)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 11,409 Value ($000) $1,869 Avg Close $156.63 Range $134.19 - $174.01

Q2 2025

Shares 4,385 Value ($000) $545 Avg Close $127.25 Range $102.97 - $148.94

Q2 2024

Shares 3,748 Value ($000) $472 Avg Close $156.74 Range $113.50 - $184.98

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	11,409	$1,869	$156.63	$134.19 - $174.01
Q2 2025	4,385	$545	$127.25	$102.97 - $148.94
Q2 2024	3,748	$472	$156.74	$113.50 - $184.98