REPLIGEN CORP

Ticker: RGEN CUSIP: 759916109 Class: Common Stock

Holocene Advisors, LP's Holding History (CIK: 0001700574)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 961,040 Value ($000) $157,476 Avg Close $156.63 Range $134.19 - $174.01

Q3 2025

Shares 1,377,104 Value ($000) $184,077 Avg Close $121.47 Range $110.77 - $135.57

Q2 2025

Shares 936,814 Value ($000) $116,521 Avg Close $127.25 Range $102.97 - $148.94

Q1 2025

Shares 959,982 Value ($000) $122,148 Avg Close $153.93 Range $125.39 - $182.52

Q4 2024

Shares 311,104 Value ($000) $44,780 Avg Close $143.40 Range $121.52 - $161.24

Q1 2024

Shares 342,388 Value ($000) $62,972 Avg Close $190.44 Range $167.40 - $211.13

Q4 2023

Shares 304,914 Value ($000) $54,824 Avg Close $155.67 Range $110.45 - $188.31

Q2 2021

Shares 256,780 Value ($000) $51,258 Avg Close $193.99 Range $162.29 - $223.03

Q1 2021

Shares 180,732 Value ($000) $35,136 Avg Close $205.03 Range $173.09 - $228.84

Q4 2020

Shares 230,477 Value ($000) $44,166 Avg Close $181.94 Range $146.52 - $212.55

Q3 2020

Shares 288,839 Value ($000) $42,615 Avg Close $142.94 Range $120.12 - $159.97

Q1 2018

Shares 6,547 Value ($000) $237 Avg Close $35.17 Range $29.56 - $37.82

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	961,040	$157,476	$156.63	$134.19 - $174.01
Q3 2025	1,377,104	$184,077	$121.47	$110.77 - $135.57
Q2 2025	936,814	$116,521	$127.25	$102.97 - $148.94
Q1 2025	959,982	$122,148	$153.93	$125.39 - $182.52
Q4 2024	311,104	$44,780	$143.40	$121.52 - $161.24
Q1 2024	342,388	$62,972	$190.44	$167.40 - $211.13
Q4 2023	304,914	$54,824	$155.67	$110.45 - $188.31
Q2 2021	256,780	$51,258	$193.99	$162.29 - $223.03
Q1 2021	180,732	$35,136	$205.03	$173.09 - $228.84
Q4 2020	230,477	$44,166	$181.94	$146.52 - $212.55
Q3 2020	288,839	$42,615	$142.94	$120.12 - $159.97
Q1 2018	6,547	$237	$35.17	$29.56 - $37.82