REPLIGEN CORP

Ticker: RGEN CUSIP: 759916109 Class: Common Stock

Polar Capital Holdings Plc's Holding History (CIK: 0001837309)

Note: Option positions (PUT/CALL) are excluded.

Q4 2025

Shares 1,230 Value ($000) $202 Avg Close $156.63 Range $134.19 - $174.01

Q4 2022

Shares 2,500 Value ($000) $423 Avg Close $181.39 Range $158.58 - $225.62

Q3 2022

Shares 2,500 Value ($000) $468 Avg Close $210.87 Range $157.33 - $262.26

Q4 2020

Shares 1,509 Value ($000) $289 Avg Close $181.94 Range $146.52 - $212.55

Period	Shares	Value ($000)	Average Close	Price Range
Q4 2025	1,230	$202	$156.63	$134.19 - $174.01
Q4 2022	2,500	$423	$181.39	$158.58 - $225.62
Q3 2022	2,500	$468	$210.87	$157.33 - $262.26
Q4 2020	1,509	$289	$181.94	$146.52 - $212.55