SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

FRED ALGER MANAGEMENT, LLC's Holding History (CIK: 0000003520)

Note: Option positions (PUT/CALL) are excluded.

Q2 2017
Shares 8,500 Value ($000) $1,405 Avg Close — Range —
Q1 2017
Shares 14,000 Value ($000) $2,439 Avg Close — Range —
Q4 2016
Shares 17,000 Value ($000) $2,896 Avg Close — Range —
Q3 2016
Shares 25,600 Value ($000) $4,963 Avg Close — Range —
Q2 2016
Shares 25,600 Value ($000) $4,712 Avg Close — Range —
Q1 2016
Shares 44,757 Value ($000) $7,694 Avg Close — Range —
Q4 2015
Shares 242,856 Value ($000) $49,786 Avg Close — Range —
Q3 2015
Shares 172,501 Value ($000) $35,402 Avg Close — Range —
Q2 2015
Shares 170,886 Value ($000) $41,267 Avg Close — Range —
Q1 2015
Shares 230,786 Value ($000) $55,225 Avg Close — Range —
Q4 2014
Shares 189,521 Value ($000) $40,280 Avg Close — Range —
Q3 2014
Shares 12,729 Value ($000) $3,297 Avg Close — Range —
Q1 2014
Shares 5,450 Value ($000) $809 Avg Close — Range —
Q4 2013
Shares 14,250 Value ($000) $2,013 Avg Close — Range —
Q3 2013
Shares 36,150 Value ($000) $4,334 Avg Close — Range —
Q2 2013
Shares 34,100 Value ($000) $3,243 Avg Close — Range —