SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

FIRST MANHATTAN CO. LLC.'s Holding History (CIK: 0000728083)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 495 Value ($000) $89 Avg Close — Range —
Q2 2018
Shares 531 Value ($000) $89 Avg Close — Range —
Q1 2018
Shares 538 Value ($000) $80 Avg Close — Range —
Q4 2017
Shares 538 Value ($000) $83 Avg Close — Range —
Q3 2017
Shares 1,233 Value ($000) $188 Avg Close — Range —
Q2 2017
Shares 1,219 Value ($000) $201 Avg Close — Range —
Q1 2017
Shares 1,255 Value ($000) $218 Avg Close — Range —
Q4 2016
Shares 1,443 Value ($000) $245 Avg Close — Range —
Q3 2016
Shares 1,706 Value ($000) $330 Avg Close — Range —
Q2 2016
Shares 6,994 Value ($000) $1,287 Avg Close — Range —