SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

CAISSE DE DEPOT ET PLACEMENT DU QUEBEC's Holding History (CIK: 0000898286)

Note: Option positions (PUT/CALL) are excluded.

Q1 2017
Shares 1,205 Value ($000) $210 Avg Close — Range —
Q4 2016
Shares 1,205 Value ($000) $205 Avg Close — Range —
Q3 2016
Shares 1,205 Value ($000) $234 Avg Close — Range —
Q2 2016
Shares 1,205 Value ($000) $222 Avg Close — Range —