SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

BLAIR WILLIAM & CO/IL's Holding History (CIK: 0000902367)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 2,987 Value ($000) $541 Avg Close — Range —
Q2 2018
Shares 3,484 Value ($000) $588 Avg Close — Range —
Q1 2018
Shares 3,556 Value ($000) $531 Avg Close — Range —
Q4 2017
Shares 4,644 Value ($000) $720 Avg Close — Range —
Q3 2017
Shares 12,433 Value ($000) $1,904 Avg Close — Range —
Q2 2017
Shares 15,409 Value ($000) $2,547 Avg Close — Range —
Q1 2017
Shares 16,498 Value ($000) $2,954 Avg Close — Range —
Q4 2016
Shares 16,642 Value ($000) $2,836 Avg Close — Range —
Q3 2016
Shares 20,918 Value ($000) $4,055 Avg Close — Range —
Q2 2016
Shares 16,425 Value ($000) $3,023 Avg Close — Range —
Q1 2016
Shares 8,577 Value ($000) $1,474 Avg Close — Range —
Q4 2015
Shares 10,073 Value ($000) $2,065 Avg Close — Range —
Q3 2015
Shares 61,883 Value ($000) $12,700 Avg Close — Range —
Q2 2015
Shares 216,639 Value ($000) $52,316 Avg Close — Range —
Q1 2015
Shares 17,312 Value ($000) $4,142 Avg Close — Range —
Q4 2014
Shares 15,324 Value ($000) $3,257 Avg Close — Range —
Q3 2014
Shares 991 Value ($000) $256 Avg Close — Range —
Q2 2014
Shares 17,584 Value ($000) $4,141 Avg Close — Range —
Q1 2014
Shares 17,861 Value ($000) $2,652 Avg Close — Range —
Q4 2013
Shares 18,772 Value ($000) $2,652 Avg Close — Range —
Q3 2013
Shares 21,614 Value ($000) $2,591 Avg Close — Range —
Q2 2013
Shares 21,292 Value ($000) $2,025 Avg Close — Range —