SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

MANUFACTURERS LIFE INSURANCE COMPANY, THE's Holding History (CIK: 0000928047)

Note: Option positions (PUT/CALL) are excluded.

Q2 2018
Shares 27,673 Value ($000) $4,671 Avg Close — Range —
Q1 2018
Shares 1,847,810 Value ($000) $276,045 Avg Close — Range —
Q4 2017
Shares 1,848,471 Value ($000) $286,735 Avg Close — Range —
Q3 2017
Shares 1,846,263 Value ($000) $282,736 Avg Close — Range —
Q2 2017
Shares 496,303 Value ($000) $82,024 Avg Close — Range —
Q1 2017
Shares 496,083 Value ($000) $86,433 Avg Close — Range —
Q4 2016
Shares 479,443 Value ($000) $81,688 Avg Close — Range —
Q3 2016
Shares 459,994 Value ($000) $89,175 Avg Close — Range —
Q2 2016
Shares 385,733 Value ($000) $71,006 Avg Close — Range —
Q1 2016
Shares 332,075 Value ($000) $55,955 Avg Close — Range —
Q4 2015
Shares 1,107 Value ($000) $227 Avg Close — Range —
Q3 2015
Shares 1,000 Value ($000) $205 Avg Close — Range —
Q2 2015
Shares 1,000 Value ($000) $241 Avg Close — Range —
Q1 2015
Shares 1,000 Value ($000) $239 Avg Close — Range —
Q4 2014
Shares 900 Value ($000) $191 Avg Close — Range —
Q3 2014
Shares 900 Value ($000) $233 Avg Close — Range —
Q2 2014
Shares 45,305 Value ($000) $10,669 Avg Close — Range —
Q1 2014
Shares 42,200 Value ($000) $6,268 Avg Close — Range —
Q4 2013
Shares 49,978 Value ($000) $7,061 Avg Close — Range —
Q3 2013
Shares 60,284 Value ($000) $7,227 Avg Close — Range —
Q2 2013
Shares 53,851 Value ($000) $5,122 Avg Close — Range —