SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

KINGDON CAPITAL MANAGEMENT, L.L.C.'s Holding History (CIK: 0001000097)

Note: Option positions (PUT/CALL) are excluded.

Q2 2017
Shares 62,935 Value ($000) $10,401 Avg Close — Range —
Q4 2016
Shares 11,900 Value ($000) $2,028 Avg Close — Range —