SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

D. E. Shaw & Co., Inc.'s Holding History (CIK: 0001009207)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 1,584,224 Value ($000) $275,718 Avg Close — Range —
Q3 2018
Shares 517,289 Value ($000) $93,769 Avg Close — Range —
Q2 2018
Shares 58,760 Value ($000) $9,919 Avg Close — Range —
Q1 2018
Shares 474,673 Value ($000) $70,911 Avg Close — Range —
Q4 2017
Shares 596,638 Value ($000) $92,550 Avg Close — Range —
Q3 2017
Shares 230,917 Value ($000) $35,363 Avg Close — Range —
Q2 2017
Shares 285,215 Value ($000) $47,137 Avg Close — Range —
Q1 2017
Shares 347,201 Value ($000) $60,493 Avg Close — Range —
Q4 2016
Shares 3,609 Value ($000) $615 Avg Close — Range —
Q2 2016
Shares 273,132 Value ($000) $50,278 Avg Close — Range —
Q1 2016
Shares 327,279 Value ($000) $56,259 Avg Close — Range —
Q4 2015
Shares 437,447 Value ($000) $89,677 Avg Close — Range —
Q3 2015
Shares 491,376 Value ($000) $100,845 Avg Close — Range —
Q2 2015
Shares 563,048 Value ($000) $135,971 Avg Close — Range —
Q1 2015
Shares 300,482 Value ($000) $71,902 Avg Close — Range —
Q4 2014
Shares 277,400 Value ($000) $58,959 Avg Close — Range —
Q3 2014
Shares 193,584 Value ($000) $50,148 Avg Close — Range —
Q2 2014
Shares 73,969 Value ($000) $17,419 Avg Close — Range —
Q1 2014
Shares 134,394 Value ($000) $19,962 Avg Close — Range —
Q4 2013
Shares 359,639 Value ($000) $50,813 Avg Close — Range —
Q3 2013
Shares 527,703 Value ($000) $63,266 Avg Close — Range —
Q2 2013
Shares 453,546 Value ($000) $43,137 Avg Close — Range —