SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

EVERETT HARRIS & CO /CA/'s Holding History (CIK: 0001009254)

Note: Option positions (PUT/CALL) are excluded.

Q1 2018
Shares 6,503 Value ($000) $971 Avg Close — Range —
Q4 2017
Shares 6,305 Value ($000) $978 Avg Close — Range —
Q3 2017
Shares 6,467 Value ($000) $990 Avg Close — Range —
Q2 2017
Shares 6,767 Value ($000) $1,118 Avg Close — Range —
Q1 2017
Shares 10,041 Value ($000) $1,749 Avg Close — Range —
Q4 2016
Shares 11,854 Value ($000) $2,020 Avg Close — Range —
Q3 2016
Shares 19,507 Value ($000) $3,782 Avg Close — Range —
Q2 2016
Shares 22,226 Value ($000) $4,091 Avg Close — Range —