SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

NATIXIS ADVISORS, L.P.'s Holding History (CIK: 0001018331)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 10,950 Value ($000) $1,905 Avg Close — Range —
Q3 2018
Shares 50,086 Value ($000) $9,078 Avg Close — Range —
Q2 2018
Shares 52,894 Value ($000) $8,928 Avg Close — Range —
Q1 2018
Shares 61,793 Value ($000) $9,231 Avg Close — Range —
Q4 2017
Shares 73,804 Value ($000) $11,448 Avg Close — Range —
Q3 2017
Shares 66,276 Value ($000) $10,148 Avg Close — Range —
Q2 2017
Shares 58,675 Value ($000) $9,698 Avg Close — Range —
Q1 2017
Shares 57,802 Value ($000) $10,071 Avg Close — Range —
Q4 2016
Shares 46,068 Value ($000) $7,848 Avg Close — Range —
Q3 2016
Shares 48,087 Value ($000) $9,322 Avg Close — Range —
Q2 2016
Shares 41,084 Value ($000) $7,563 Avg Close — Range —
Q1 2016
Shares 34,151 Value ($000) $5,870 Avg Close — Range —
Q4 2015
Shares 27,818 Value ($000) $5,703 Avg Close — Range —
Q3 2015
Shares 29,101 Value ($000) $5,973 Avg Close — Range —
Q2 2015
Shares 29,856 Value ($000) $7,210 Avg Close — Range —
Q1 2015
Shares 32,185 Value ($000) $7,702 Avg Close — Range —
Q4 2014
Shares 21,423 Value ($000) $4,553 Avg Close — Range —
Q3 2014
Shares 18,507 Value ($000) $4,795 Avg Close — Range —
Q2 2014
Shares 36,041 Value ($000) $8,487 Avg Close — Range —
Q1 2014
Shares 25,329 Value ($000) $3,762 Avg Close — Range —
Q4 2013
Shares 15,239 Value ($000) $2,153 Avg Close — Range —
Q3 2013
Shares 12,193 Value ($000) $1,462 Avg Close — Range —
Q2 2013
Shares 11,368 Value ($000) $1,081 Avg Close — Range —