SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

ARROWSTREET CAPITAL, LIMITED PARTNERSHIP's Holding History (CIK: 0001164508)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 2,396,296 Value ($000) $417,051 Avg Close — Range —
Q3 2018
Shares 1,399,098 Value ($000) $253,614 Avg Close — Range —
Q2 2018
Shares 453,989 Value ($000) $76,634 Avg Close — Range —
Q3 2017
Shares 103,800 Value ($000) $15,896 Avg Close — Range —
Q2 2017
Shares 916,378 Value ($000) $151,450 Avg Close — Range —
Q1 2017
Shares 1,108,878 Value ($000) $193,200 Avg Close — Range —