SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

SECTORAL ASSET MANAGEMENT INC's Holding History (CIK: 0001274413)

Note: Option positions (PUT/CALL) are excluded.

Q3 2018
Shares 1,300 Value ($000) $236 Avg Close — Range —
Q2 2018
Shares 4,500 Value ($000) $760 Avg Close — Range —
Q1 2017
Shares 173,679 Value ($000) $30,260 Avg Close — Range —
Q4 2016
Shares 158,158 Value ($000) $26,947 Avg Close — Range —
Q3 2016
Shares 166,093 Value ($000) $32,199 Avg Close — Range —
Q2 2016
Shares 148,424 Value ($000) $27,322 Avg Close — Range —
Q1 2016
Shares 405,347 Value ($000) $69,679 Avg Close — Range —
Q4 2015
Shares 164,674 Value ($000) $33,758 Avg Close — Range —
Q3 2015
Shares 122,056 Value ($000) $25,050 Avg Close — Range —
Q2 2015
Shares 113,812 Value ($000) $27,484 Avg Close — Range —
Q1 2015
Shares 248,859 Value ($000) $59,549 Avg Close — Range —
Q4 2014
Shares 236,124 Value ($000) $50,186 Avg Close — Range —
Q3 2014
Shares 71,536 Value ($000) $18,531 Avg Close — Range —
Q2 2014
Shares 230,636 Value ($000) $54,312 Avg Close — Range —
Q1 2014
Shares 391,197 Value ($000) $58,104 Avg Close — Range —
Q4 2013
Shares 468,759 Value ($000) $66,231 Avg Close — Range —
Q3 2013
Shares 411,586 Value ($000) $49,345 Avg Close — Range —
Q2 2013
Shares 492,333 Value ($000) $46,826 Avg Close — Range —