SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

Douglass Winthrop Advisors, LLC's Holding History (CIK: 0001308527)

Note: Option positions (PUT/CALL) are excluded.

Q3 2016
Shares 2,892 Value ($000) $561 Avg Close — Range —
Q2 2016
Shares 2,826 Value ($000) $520 Avg Close — Range —