SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

CAPITAL FUND MANAGEMENT S.A.'s Holding History (CIK: 0001323645)

Note: Option positions (PUT/CALL) are excluded.

Q4 2018
Shares 19,643 Value ($000) $3,419 Avg Close — Range —
Q3 2018
Shares 19,643 Value ($000) $3,561 Avg Close — Range —
Q2 2018
Shares 21,049 Value ($000) $3,553 Avg Close — Range —
Q1 2018
Shares 134,549 Value ($000) $20,100 Avg Close — Range —
Q4 2017
Shares 142,608 Value ($000) $22,121 Avg Close — Range —
Q3 2017
Shares 200,608 Value ($000) $30,721 Avg Close — Range —
Q2 2017
Shares 170,008 Value ($000) $28,097 Avg Close — Range —
Q1 2017
Shares 282,931 Value ($000) $49,295 Avg Close — Range —
Q4 2016
Shares 19,597 Value ($000) $3,339 Avg Close — Range —
Q1 2016
Shares 371,232 Value ($000) $63,815 Avg Close — Range —
Q4 2015
Shares 121,610 Value ($000) $24,930 Avg Close — Range —
Q3 2015
Shares 1,100 Value ($000) $226 Avg Close — Range —
Q2 2015
Shares 63,944 Value ($000) $15,442 Avg Close — Range —
Q1 2015
Shares 141,234 Value ($000) $33,796 Avg Close — Range —
Q4 2014
Shares 36,599 Value ($000) $7,779 Avg Close — Range —
Q3 2014
Shares 1,096 Value ($000) $284 Avg Close — Range —
Q1 2014
Shares 47,899 Value ($000) $7,114 Avg Close — Range —
Q3 2013
Shares 2,749 Value ($000) $330 Avg Close — Range —
Q2 2013
Shares 84,401 Value ($000) $8,027 Avg Close — Range —