SHIRE PLC

CUSIP: 82481R106 Class: COMMON STOCK-FO

Zurcher Kantonalbank (Zurich Cantonalbank)'s Holding History (CIK: 0001368163)

Note: Option positions (PUT/CALL) are excluded.

Q2 2014
Shares 11,000 Value ($000) $2,590 Avg Close — Range —
Q1 2014
Shares 11,000 Value ($000) $1,634 Avg Close — Range —
Q1 2013
Shares 56,720 Value ($000) $5,182 Avg Close — Range —
Q4 2012
Shares 57,400 Value ($000) $5,291 Avg Close — Range —
Q3 2012
Shares 48,010 Value ($000) $4,258 Avg Close — Range —
Q2 2012
Shares 44,280 Value ($000) $3,825 Avg Close — Range —
Q1 2012
Shares 37,190 Value ($000) $3,524 Avg Close — Range —
Q4 2011
Shares 27,200 Value ($000) $2,826 Avg Close — Range —